Protein Alignment Pgant6 and Pgant5

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_061512049.1
• Gene: Pgant5 / 1275461
• VectorBaseID: AGAMI1_012697
• Length: 655
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 235/659 - (35%)
• Similarity: 345/659 - (52%)
• Gaps: 99/659 - (15%)

  Fly     1 MRRPNLKWIVKASLL-LLISLTLFVLI---------TSWISSTPYTNKPVHHGVEPVPEKAGLSG 55
            :|....:.:|..||: |||.:.|.|..         :||:...                    :|
Mosquito    14 IRTNTCRIVVLTSLVWLLIDVILIVKYADCPSTGGGSSWLCKR--------------------NG 58

  Fly    56 D-VKVKVP-AIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDN------------PHPADDE- 105
            | ..|:|| |.:|.:.|:......::||    |.:.|.::...:|            ...||..
Mosquito    59 DGYDVEVPNAARQSQQQRRAAAPEDDDP----IVDAEEIDTNSNNFGDPGGYGGGGGGRDADSSM 119

  Fly   106 PQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGF 170
            |:....:||           |.|.....:.::..|.  ||.||...: ..:|::|.|....||.|
Mosquito   120 PRTYRPQEL-----------KKWRQAPTVAENYGRP--GEMGKPVKI-PANQQELMKEKFKENQF 170

  Fly   171 NALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMK 235
            |.|.||.|.:|||:.|:||..|:||.|.|||||.|::|:|:||..|.|:|::.|:|||||..|:|
Mosquito   171 NLLASDMIWLNRSLTDVRHHDCKKKHYPAKLPTTSIVIVFHNEAWSTLLRTIWSVINRSPRPLLK 235

  Fly   236 EIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEA 300
            |||||||.|:||:||::||.|:........|:|..:|:|||.||..||::...:|:.|||:|.|.
Mosquito   236 EIILVDDASEREHLGRQLEEYVRTLPVPTFVLRTGKRSGLIRARLLGAKHVKGQVITFLDAHCEC 300

  Fly   301 NYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWE--FFYKRLPLLPEDLKH 363
            ...||.|||..|.|:::|.|||.||||....|.|....:...|.|:|:  |.:.|:|......::
Mosquito   301 TEGWLEPLLARIVLDRKTVVCPIIDVISDETFEYVTASDQTWGGFNWKLNFRWYRVPAREMQRRN 365

  Fly   364 --PADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGH 426
              ...|.::|.||||||:|.|::|:|:|.||||:||||||..|:||:||.|||.:..:|||.:||
Mosquito   366 HDRTAPLRTPTMAGGLFSIDRDYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEISPCSHVGH 430

  Fly   427 IYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNC 491
            ::|....:.......:.:.||..||||||:||:|.:.|....|. .....||::|::|:|.:|.|
Mosquito   431 VFRDKSPYTFPGGVANIVLKNAARVAEVWLDEWKEFYYQMSPGA-RKASAGDVSERRALRERLKC 494

  Fly   492 KSFKWFMEEVAFDLMKTYP----PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC---- 548
            |||:|::|.:       ||    |:|  .|.:|.::||...| ||||:|||.:.|:|...|
Mosquito   495 KSFRWYLENI-------YPESQMPLD--YYFLGEIRNVKTHN-CLDTMGRKSNEKIGSSYCHGLG 549

  Fly   549 ADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLK 613
            .:.:          .::.:..::.....|||..  :|..||.|..||..||||.|.||...|.:|
Mosquito   550 GNQV----------FAYTKRHQIMSDDNCLDAS--NALGPVNLVRCHGMGGNQEWIYDDEEKTIK 602

  Fly   614 HGTEGRRCL 622
            |...| .||
Mosquito   603 HVNSG-NCL 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	132/300 (44%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	37/112 (33%)
Pgant5	XP_061512049.1	None