Protein Alignment Pgant6 and Pgant35A

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_313714.6
• Gene: Pgant35A / 1274571
• VectorBaseID: AGAMI1_002567
• Length: 663
• Species: Anopheles gambiae
• Alignment Length: 672
• Identity: 216/672 - (32%)
• Similarity: 317/672 - (47%)
• Gaps: 129/672 - (19%)

  Fly     1 MRRPNLKW-IVKASLLLLISLTLFVLITSW-ISSTPYTNKPVHHGVEPVPEKAGLSGDVKVKVPA 63
            |...:..| ::.|||...||:.|:     | :|:|| ||            .||.|.....|.|.
Mosquito    16 MTNRSFLWGVMAASLTWSISIYLY-----WNLSNTP-TN------------GAGSSEQRLAKAPT 62

  Fly    64 IKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKK-- 126
                                              :...|:|..|...:.:..:...:|..:.|
Mosquito    63 ----------------------------------SATAAEDTRQLILRNQNSLIGASDERLHKKA 93

  Fly   127 -DWHD---------YT-FM-EKDAKRV----------------GLGEGGKASTLDDESQRDLEKR 163
             .|.:         |. || ||:.:|:                |..|.|.....:::..||:..|
Mosquito    94 SKWAEKGKSLFKEKYARFMHEKEKRRISHRLIDELQPMLIQPNGTDEFGMVQNSEEQFIRDIGYR 158

  Fly   164 MSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINR 228
               ::.||.|:|:.:...|.:||.||.||:.:.|...||..||::.||||:|..|:||:|:::.|
Mosquito   159 ---KHAFNVLVSNKLGPFRPIPDTRHKLCQAQVYDKVLPVASVVMCFYNEHLETLVRSIHTVLKR 220

  Fly   229 SPPELMKEIILVDDHSDREYL--GKELETYIAE-HFKWVRVVRLPRRTGLIGARAAGARNATAEV 290
            :|..|:||:|||||.||.|.|  |.:||..:|: ....||::|...|.||:.:|..||||||.:|
Mosquito   221 TPAYLLKELILVDDCSDFEDLTVGGQLEKELAQLGTNKVRLLRNTDREGLMRSRVYGARNATGQV 285

  Fly   291 LIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLP 355
            |||||||:|.|.:|:.|||..|..::.....|.||:|:...|.|.|... .||.|:|...:|...
Mosquito   286 LIFLDSHIEVNVDWIEPLLARIKHDRTILAMPVIDIINSDTFVYTASPL-VRGGFNWGLHFKWDN 349

  Fly   356 LLPEDLKHPAD---PFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMY 417
            |....|:...|   ||.||.||||||||.|.:|.|||.||.|:|:||||..|:||:.|.|||.:.
Mosquito   350 LPKGSLERDTDFVGPFNSPTMAGGLFAIDRAYFKELGEYDMGMDVWGGENLEISFRAWQCGGSIE 414

  Fly   418 DAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQ 482
            ..|||||||::| .|....||...|.:.:|..|:|.||||:|..|.|......:. |..|:::|:
Mosquito   415 LLPCSRIGHVFR-KRRPYGSPDGQDTMIRNSLRLAHVWMDDYIRYFYEQQPQAHH-VPYGNVSER 477

  Fly   483 KAIRTKLNCKSFKWFMEEVAFDLM------------KTYPPVDP-----PSYAMGALQNVGNQNL 530
            :.:|.:|.||.|:|:::.:...|.            .|.|..:|     .:|.......:.|.:|
Mosquito   478 QRLRERLGCKPFRWYLDNIYPQLRVPGEKTSSDARDATQPKFEPWHSRKRNYVASFQIRLSNSSL 542

  Fly   531 CLDT-LGR-----KKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPV 589
            ||.| |..     ||.:.:.:..|   ::...:|  |..:.|.:|.|.:.. |||..........
Mosquito   543 CLSTELDSEKSLWKKGSGLVLQPC---LRVKHQT--WYETEKSELVLGQLL-CLDAPSSATKGRP 601

  Fly   590 WLWDCHSQGGNQYWYYDYRHKQ 611
            .|..||..||:|.|    :|::
Mosquito   602 KLNKCHEMGGDQAW----KHRK 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	135/302 (45%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	26/103 (25%)
Pgant35A	XP_313714.6	None