Protein Alignment Pgant6 and Galnt2

DIOPT Version :9

• Sequence 1: NP_001261342.1
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_644678.2
• Gene: Galnt2 / 108148
• MGIID: 894694
• Length: 570
• Species: Mus musculus
• Alignment Length: 575
• Identity: 199/575 - (34%)
• Similarity: 281/575 - (48%)
• Gaps: 87/575 - (15%)

  Fly   117 AAPADASVKKDWHDYTFMEK--------DAKRVGLG--EGGKASTLDDESQRDLEKRM------- 164
            |....|..|.||:|...::|        |.|..|:.  ..||....|...:..:...|
Mouse    33 AGGGGAGRKGDWNDIDSIKKKDLHHSRGDEKAQGVETLPPGKVRWPDFNQEAYVGGTMVRSGQDP 97

  Fly   165 SLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRS 229
            ...|.||.:.||.:.::|.:||.||..|::|::...||..||:|.|:||..|.|:|:|.|::.||
Mouse    98 YARNKFNQVESDKLHMDRGIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKRS 162

  Fly   230 PPELMKEIILVDDHS----DREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEV 290
            ||.|:||||||||:|    |...|||         .:.|||:|..||.||:.:|..||..|.|:|
Mouse   163 PPHLIKEIILVDDYSNDPEDGALLGK---------IEKVRVLRNDRREGLMRSRVRGADAAQAKV 218

  Fly   291 LIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLP 355
            |.|||||.|.|..||.||||.:|.::...|.|.||||:..||.|.......:|.|||...:|...
Mouse   219 LTFLDSHCECNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDY 283

  Fly   356 LLPEDLK----HPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEM 416
            :.||..:    :|..|.|:|::|||||.:.:.:|.|||.||..:|:||||..|:||::|.|||.:
Mouse   284 MTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLEISFRVWQCGGSL 348

  Fly   417 YDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTE 481
            ...||||:||::|....:......|....:|.:|.|||||||||::.|:..... .:|..|::..
Mouse   349 EIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKHFYYAAVPSA-RNVPYGNIQS 412

  Fly   482 QKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSY---AMGALQNVGNQNLCLDTLGRKKHNKM 543
            :..:|.||.||.|||:::.|       ||.:..|.:   |.||||...|   ||||||......:
Mouse   413 RLELRKKLGCKPFKWYLDNV-------YPELRVPDHQDIAFGALQQGTN---CLDTLGHFADGVV 467

  Fly   544 GMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYR 608
            |:|.|    ......|.|.|:  ::..::....||.|......:.:.|..|......|.|.....
Mouse   468 GIYEC----HNAGGNQEWALT--KEKSVKHMDLCLTVVDRSPGSLIRLQGCRENDSRQKWEQIEG 526

  Fly   609 HKQLKHGTEGRRCLELLPFSQEVVANKCDTDNR----------------FQQWNF 647
            :.:|:|                |.:|.| .|:|                .|||.|
Mouse   527 NSKLRH----------------VGSNLC-LDSRTAKSGGLSVEVCGPALSQQWKF 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	100/221 (45%)
		pp-GalNAc-T	205..502	CDD:133004	131/304 (43%)
		RICIN	520..647	CDD:238092	34/142 (24%)
		Ricin_B_lectin	520..645	CDD:279046	32/140 (23%)
Galnt2	NP_644678.2	Catalytic subdomain A	134..239		58/113 (51%)
		pp-GalNAc-T	138..433	CDD:133004	132/311 (42%)
		Catalytic subdomain B	299..361		32/61 (52%)
		Ricin_B_lectin	445..562	CDD:279046	33/142 (23%)
		RICIN	455..564	CDD:238092	29/131 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810