DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and LOC103910015

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_009296677.3	Gene:	LOC103910015 / 103910015	-ID:	-	Length:	595	Species:	Danio rerio

Alignment Length:	585	Identity:	277/585 - (47%)
Similarity:	362/585 - (61%)	Gaps:	36/585 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 VEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDES 156
            :|..:|...|.......|.|:..:.....|...|||||||..:..||.|.|.||.|:...|.|..
Zfish    29 LERRLDAEEPEGGAGLAQMQKVNRKQVLKDGVRKKDWHDYAAIRSDAARTGAGEQGRPYPLTDAE 93

  Fly   157 QRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRS 221
            :.|...|   |||||..:||.|::|||:||||||.|:.|.|.|.||..||||.|:||..|.|:|:
Zfish    94 RVDQAYR---ENGFNIFVSDRIALNRSLPDIRHPNCKLKLYTADLPNTSVIIPFHNEGWSSLLRT 155

  Fly   222 VHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNA 286
            |||:::||||.|:.|||||||.||:.:|...||.|:....| ||::|..:|.|||..|..||..|
Zfish   156 VHSVLDRSPPSLIAEIILVDDFSDKGHLKAPLEQYMVRLPK-VRILRTQKREGLIRTRLLGAAAA 219

  Fly   287 TAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQ-DEGARGAFDWEFF 350
            ..:|:.|||||.|||.|||||||:.||.|::|.|||.||||||.||.|..| .:..|||||||.:
Zfish   220 RGQVITFLDSHCEANVNWLPPLLDRIAQNRKTIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMY 284

  Fly   351 YKRLPLLPEDL--KHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCG 413
            |||:| :|..|  ..|::||.||:|||||||:.|::||||||||.||:||||||||:|||:||||
Zfish   285 YKRIP-IPAQLAKPDPSEPFDSPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCG 348

  Fly   414 GEMYDAPCSRIGHIYRGPRNHQPSPRK---GDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVD 475
            |.|.|.||||:|||||     :..|.|   |..|.:|.|||||||||||..:||..... |..:.
Zfish   349 GRMEDIPCSRVGHIYR-----KYVPYKVPGGVSLARNLKRVAEVWMDEYAEFLYQRRPE-YRHLS 407

  Fly   476 PGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKH 540
            .||:::||.:|::|:|:||:|||||||:||.|.||||:||:.|.|.|:|||. .||:::    ||
Zfish   408 SGDVSQQKELRSRLHCRSFRWFMEEVAWDLPKHYPPVEPPAAAWGELRNVGT-GLCVES----KH 467

  Fly   541 NKMG----MYACADNIKTP--QRTQFWELSWKRDLR----LRRKKECLDVQIWDANAPVWLWDCH 595
            ...|    :..|..:...|  ...|.:...|::|:|    |..||.|.|..  ..|:||.|:|||
Zfish   468 FSSGSPIRLEPCLRSRGEPSWSHGQVFTFGWRQDIRVGDPLHTKKVCFDAV--SHNSPVTLYDCH 530

  Fly   596 SQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQ 660
            ...|||.|.| .:.:.|.|.. ...|:......:.::.:.||..:..|||.|.:.|.:.||:::|
Zfish   531 GMKGNQLWAY-RKDRSLFHPI-SNSCVSADAAQKRLLMSSCDASSSSQQWVFQNTNSSVLDSFNQ 593

Fly 661 660
Zfish 594 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	128/216 (59%)
		pp-GalNAc-T	205..502	CDD:133004	172/302 (57%)
		RICIN	520..647	CDD:238092	41/136 (30%)
		Ricin_B_lectin	520..645	CDD:279046	39/134 (29%)
LOC103910015	XP_009296677.3	pp-GalNAc-T	139..434	CDD:133004	172/302 (57%)
LOC103910015	XP_009296677.3	Ricin_B_lectin	450..578	CDD:306998	40/136 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2739
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	506	1.000	Inparanoid score	I1301
OMA	1	1.010	-	-		QHG48703
OrthoDB	1	1.010	-	-		D144590at33208
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	1	1.000	-	-		mtm6424
orthoMCL	1	0.900	-	-		OOG6_104854
Panther	1	1.100	-	-	LDO	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1309
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.980