Protein Alignment Pgant6 and POC1B-GALNT4

DIOPT Version :9

• Sequence 1: NP_001261342.1
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001186710.1
• Gene: POC1B-GALNT4 / 100528030
• HGNCID: 42957
• Length: 575
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 198/535 - (37%)
• Similarity: 283/535 - (52%)
• Gaps: 80/535 - (14%)

  Fly   122 ASVKKDWHDYT---FMEKDAKRVGLGEGGKASTL---DDE--SQRDLEKRMSLENGFNALLSDSI 178
            :.::|:..|.:   :.:..|....|||.||||.|   :||  .|.:|.:|.::    |..|||.|
Human    47 SDLQKNTEDLSRPLYKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAI----NIYLSDRI 107

  Fly   179 SVNRSVPDIRHPLCRKKEY-VAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDD 242
            |::|.:.|.|...|:.::: ...|||.||||.||||..|.|:|::||::..||..|:||||||||
Human   108 SLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDD 172

  Fly   243 HSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPP 307
            .|||.||..:|||||: :...||::|..:|.||:.||..||..||.:||.|||.|.|.|..||.|
Human   173 LSDRVYLKTQLETYIS-NLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEP 236

  Fly   308 LLEPIALNKRTAVCPFIDVIDHTNFHYRAQ-DEGARGAFDWE--FFYKRLPLLPEDLK-HPADPF 368
            |||.|..::...|||.||.||...|.:..| .|...|.|||.  |.:..:|....|.: ...||.
Human   237 LLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPI 301

  Fly   369 KSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRN 433
            :||.|||||||:|:::|..||.||.|:::||||..||||::|.|||::...|||.:||::
Human   302 RSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVF----- 361

  Fly   434 HQPSPRKGDYLHKNY----KRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSF 494
                |::..|...|:    .|.|||||||||.:.|:......:.. .||::|:|.:|.:|.||||
Human   362 ----PKRAPYARPNFLQNTARAAEVWMDEYKEHFYNRNPPARKEA-YGDISERKLLRERLRCKSF 421

  Fly   495 KWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQ 559
            .|:::.|..:|   :.|.|.|.: .||:::.|..:.|||            |...||..|
Human   422 DWYLKNVFPNL---HVPEDRPGW-HGAIRSRGISSECLD------------YNSPDNNPT----- 465

  Fly   560 FWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLEL 624
                                      .|.:.|:.||.|||||::.|. .:|:::..:....|.|:
Human   466 --------------------------GANLSLFGCHGQGGNQFFEYT-SNKEIRFNSVTELCAEV 503

  Fly   625 LPFSQEVVANKCDTD 639
            ......|....|..|
Human   504 PEQKNYVGMQNCPKD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	108/217 (50%)
		pp-GalNAc-T	205..502	CDD:133004	138/304 (45%)
		RICIN	520..647	CDD:238092	26/120 (22%)
		Ricin_B_lectin	520..645	CDD:279046	26/120 (22%)
POC1B-GALNT4	NP_001186710.1	WcaA	131..427	CDD:223539	141/306 (46%)
		pp-GalNAc-T	135..429	CDD:133004	138/304 (45%)
		RICIN	443..573	CDD:238092	26/120 (22%)
		Ricin_B_lectin	443..571	CDD:279046	26/120 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810