Protein Alignment Pgant6 and galnt6.2

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_031753046.1
• Gene: galnt6.2 / 100486937
• XenbaseID: XB-GENE-1000674
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 202/607 - (33%)
• Similarity: 311/607 - (51%)
• Gaps: 91/607 - (14%)

  Fly    81 PELQ---KIDEPEPVEEEVD----NPHPADDEP--QQQPQEELQMAAPADASVKKDWHDYTFMEK 136
            |:||   .:.|..||||:..    ...||:.:|  ::.||:.....|.....:|..|     .|:
 Frog    67 PKLQIMAPVQEVRPVEEKKSCLPGYYTPAELKPFMERPPQDPNSPGADGKGFIKNIW-----TEE 126

  Fly   137 DAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSV-PDIRHPLCRKKEY--V 198
            :.               :|.::..:|..     |||..||.||::|:: ||.|...|.::::  .
 Frog   127 EV---------------EEKEKGFDKHC-----FNAFASDRISLHRALGPDTRPLECIEQKFKRC 171

  Fly   199 AKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKW 263
            ..|||.|:||:|:||..|.|:|:|:|::..||..|:||||||||.|:.|||.::|:.|: :..:.
 Frog   172 PSLPTTSIIIVFHNEAWSTLLRTVYSVLYTSPAILLKEIILVDDASEDEYLKEKLDDYV-KALQI 235

  Fly   264 VRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVID 328
            |::.|...|.|||.||..||..||.|||.|||:|.|..:.||.|||..:|.:....|.|.|..|:
 Frog   236 VKIARQKERKGLITARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDHTAVVSPDITAIN 300

  Fly   329 HTNFHY-RAQDEG---ARGAFDWE--FFYKRLPLLPE-DLKHPADPFKSPIMAGGLFAISREFFW 386
            :..|.: :...:|   :||.|||.  |.::.:|...| ..|....|.|:|..|||||:||:.:|.
 Frog   301 YNTFEFGKPVQQGKMNSRGNFDWSLAFNWEAIPAADEKQRKDETYPIKTPTFAGGLFSISKAYFE 365

  Fly   387 ELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRV 451
            .:|.|||.::|||||..|:||::|.|||::...|||.:||::|....| ..|:....:.:|..|:
 Frog   366 HIGSYDEEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFRTKSPH-TFPKGTQVILRNQVRL 429

  Fly   452 AEVWMDEYKNYLYSHGD---GLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVD 513
            ||||||:||...|...:   .:.:....||::::..::..|.||:|.|::|.:..::.  .|..|
 Frog   430 AEVWMDDYKVLYYRRNEQAAKIAKEKSFGDISKRLKLKADLQCKNFTWYLENIYPEMF--VPDRD 492

  Fly   514 PPSYAMGALQNVGNQNLCLDTLGRKKHNKMG-----MYAC---ADNIKTPQRTQFWELSWKRDLR 570
            |..|  ||::|.|.|| |:|.   .::|..|     ||.|   ..|       |::|.|..::||
 Frog   493 PTYY--GAIKNEGTQN-CIDV---GENNNYGSQLPIMYPCHGMGGN-------QYFEYSTHKELR 544

  Fly   571 LRRKKE-CLDVQIWDANAPVWLWDCHSQG------GNQYWYYDYRHKQLKHGTEGRRCLELL--- 625
            ...|.: ||..:.  ...||.|.||..:|      ||:.|  ::...:|........||...
 Frog   545 HNLKTQLCLCSKY--EPGPVKLVDCQYKGQNTTVPGNEEW--EFTKDRLIRNVGSNMCLTAQGDH 605

  Fly   626 PFSQEVVANKCDTDNRFQQWNF 647
            |.:.|     |:.|:..|.|:|
 Frog   606 PSTAE-----CNPDDIDQLWSF 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	123/306 (40%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	42/151 (28%)
galnt6.2	XP_031753046.1	pp-GalNAc-T	178..483	CDD:133004	123/306 (40%)
		beta-trefoil_Ricin-like	493..623	CDD:483949	43/152 (28%)