DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and galnt13

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_005168002.1	Gene:	galnt13 / 100330695	ZFINID:	ZDB-GENE-091204-444	Length:	581	Species:	Danio rerio

Alignment Length:	543	Identity:	201/543 - (37%)
Similarity:	293/543 - (53%)	Gaps:	69/543 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 GEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVII 208
            ||.|||..:..|.| |..|.:...|.||.:.||.|::|||:||:|...|:.|.|...||..|::|
Zfish    58 GEMGKAVVIPKEEQ-DKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKTYPDDLPNTSIVI 121

  Fly   209 IFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRT 273
            :|:||..|.|:|:|||.|||||.:|:.||:||||.|:|::|.::||.|:|.....||::|:.:||
Zfish   122 VFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKEKLEDYVATLEVPVRILRMEQRT 186

  Fly   274 GLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQD 338
            |||.||..||.....:|:.|||:|.|....||.||:..|..::|..|||.||||....|.|.|..
Zfish   187 GLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGS 251

  Fly   339 EGARGAFDWEFFYKRLPLLPEDL-KHPAD---PFKSPIMAGGLFAISREFFWELGGYDEGLDIWG 399
            :...|.|:|:..::..|:...:: :...|   |.::|.||||||:|.|.:|.|:|.||.|:||||
Zfish   252 DMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWG 316

  Fly   400 GEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLY 464
            ||..|:||:||.|||.:....||.:||::|....:......|..::||.:|:|||||||:|::.|
Zfish   317 GENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFY 381

  Fly   465 SHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPS--YAMGALQNVGN 527
            ....|:.. ||.||::.:||:|..|.||.|.|::|.|       ||....|.  |::|.::|| .
Zfish   382 IISPGVVR-VDYGDVSSRKALRESLKCKPFSWYLENV-------YPDSQIPRRYYSLGEIRNV-E 437

  Fly   528 QNLCLDTLGRKKHNKMGMYAC----ADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAP 588
            .|.|:|.:|||::.|:|.:.|    .:.:          .|:..|..:|....|||..  ..|.|
Zfish   438 TNQCVDNMGRKENEKVGFFNCHGMGGNQV----------FSYTADKEIRTDDLCLDAS--RLNGP 490

  Fly   589 VWLWDCHSQGGNQY----------WYYDYRHK--------------QLKHGTEGRRCLELLPFSQ 629
            |.:..||...|||.          |.||::.:              :|:.||.|
Zfish   491 VVMLKCHHMKGNQMFEYDAEYVGKWEYDFKKRTFLHIITQSCLTISRLEDGTYG----------- 544

  Fly   630 EVVANKCDTDNRFQQWNFGSFNK 652
             .....|| |:..|.|...:|.:
Zfish   545 -PTVEYCD-DSPLQAWTLRNFTR 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	98/217 (45%)
		pp-GalNAc-T	205..502	CDD:133004	131/300 (44%)
		RICIN	520..647	CDD:238092	38/154 (25%)
		Ricin_B_lectin	520..645	CDD:279046	37/152 (24%)
galnt13	XP_005168002.1	Glyco_tranf_2_3	115..359	CDD:290369	105/243 (43%)
		pp-GalNAc-T	118..418	CDD:133004	132/307 (43%)
		RICIN	431..560	CDD:238092	38/154 (25%)
		Ricin_B_lectin	431..558	CDD:279046	37/152 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840