DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS35 and mrps35

DIOPT Version :9

Sequence 1:	NP_523893.1	Gene:	mRpS35 / 38345	FlyBaseID:	FBgn0035374	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001026839.1	Gene:	mrps35 / 503880	ZFINID:	ZDB-GENE-050809-131	Length:	330	Species:	Danio rerio

Alignment Length:	284	Identity:	129/284 - (45%)
Similarity:	176/284 - (61%)	Gaps:	15/284 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VKQQMQKRQQVRRDPITPPRTGRMAVDQDWTAVWPGPRSFHPASVPLPLRQGFTERGAAAPSKFA 113
            |:.||:.|:|...     |||.|||||||||||:|...||.|::||||:|.|:.......|:|..
Zfish    55 VRGQMKPRRQAGE-----PRTERMAVDQDWTAVYPTAASFKPSAVPLPVRMGYPVNRGVPPAKHG 114

  Fly   114 NAELMKIPNFLHLTPPAIRQQCEAIKKFCTPWPKGLETEAKWQRHFPLEVTTTDYCQSLPTIRNP 178
            |.||:||||||||||..|::.|||:|.|.|.||..|:::.|...|||::|.:.|:..|..::|||
Zfish   115 NLELIKIPNFLHLTPATIKKHCEALKPFLTEWPSALDSDEKCTEHFPIQVQSKDFVSSGLSLRNP 179

  Fly   179 EARRVTITLKLSDLKFDAHARDKFLRLVGDRYNKDTDLVTFVTDRCPQKKQNYDYALYLLTACYH 243
            :||.||:.:|.|.|..|.|||.|.::|...||.|:||.:|..||.||.::||||||:||||..||
Zfish   180 DARIVTLKVKHSSLNLDDHARKKMIKLAEKRYCKETDTLTITTDSCPLRQQNYDYAMYLLTVLYH 244

  Fly   244 ESFVTEPWEATKSEADMEVYLFERNQSK-------VSAEGILNWNAKKGAPKVVPSKSFAECVEK 301
            ||:.:|.||..|:.||||.|.::.:.|:       .|..|....:.....|:|   ..:...|.:
Zfish   245 ESWKSEAWEQEKTRADMEEYEWQDSPSQRNILETLKSIRGTEETHELLDQPEV---GEYRNSVTQ 306

  Fly   302 LINEGENEYNLGKYKEEVKKMLNI 325
            :.|.||.|.||.:|||.|||:|.:
Zfish   307 MKNHGETEENLLRYKEAVKKLLQL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS35	NP_523893.1	MRP-S28	160..281	CDD:287217	56/127 (44%)
mrps35	NP_001026839.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..73		8/22 (36%)
mrps35	NP_001026839.1	MRP-S28	178..274	CDD:287217	49/95 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586323
Domainoid	1	1.000	118	1.000	Domainoid score	I5839
eggNOG	1	0.900	-	-		E1_KOG3933
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11048
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3241
OMA	1	1.010	-	-		QHG45674
OrthoDB	1	1.010	-	-		D1339087at2759
OrthoFinder	1	1.000	-	-		FOG0007228
OrthoInspector	1	1.000	-	-		oto38876
orthoMCL	1	0.900	-	-		OOG6_107549
Panther	1	1.100	-	-	LDO	PTHR13490
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5333
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770