DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12093 and TP53I13

DIOPT Version :9

Sequence 1:	NP_647747.1	Gene:	CG12093 / 38343	FlyBaseID:	FBgn0035372	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_612358.3	Gene:	TP53I13 / 90313	HGNCID:	25102	Length:	393	Species:	Homo sapiens

Alignment Length:	129	Identity:	38/129 - (29%)
Similarity:	59/129 - (45%)	Gaps:	22/129 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 SHLPATNGPYRPMPAEYGTYSYLPPQRYVRNLAEGAIVMLYHPCAFPGQVKQLQDIVGGCLYRHL 293
            :|.|.:..|..|..:...||:.:.|.:     ||. :..||||||.|....||..:...|:....
Human    35 AHCPESLWPLPPQVSPRVTYTRVSPGQ-----AED-VTFLYHPCAHPWLKLQLALLAYACMANPS 93

  Fly   294 VSPSLALSPQRPLALLAWSRSLEMSVVDRQLAADFIQKHAKQ---------------GPLAPEE 342
            ::|..:|:..|||.|.||..:|||:.|:...||.::.:..::               || ||.|
Human    94 LTPDFSLTQDRPLVLTAWGLALEMAWVEPAWAAHWLMRRRRRKQRKKKAWIYCESLSGP-APSE 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12093	NP_647747.1	DUF3105	223..341	CDD:288196	36/126 (29%)
TP53I13	NP_612358.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..306
TP53I13	NP_612358.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..393
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2E13B
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR34179
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7425
SonicParanoid	1	1.000	-	-		X5497
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.920