DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12093 and tp53i13

DIOPT Version :9

Sequence 1:	NP_647747.1	Gene:	CG12093 / 38343	FlyBaseID:	FBgn0035372	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_001338803.3	Gene:	tp53i13 / 100002736	ZFINID:	ZDB-GENE-131121-569	Length:	465	Species:	Danio rerio

Alignment Length:	249	Identity:	78/249 - (31%)
Similarity:	113/249 - (45%)	Gaps:	59/249 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CDDGKSNLAVDF-DPNDIRDSLNFLC--ISSNHSLYQPDLSREAILTEHFL-PSAYLPPAKCLNE 224
            ||:||:||.:|. .|.::      ||  :.....|..||..     |.|.: .|.|:    |::.
Zfish    25 CDNGKTNLVMDLPGPEEL------LCQELWPQSQLNVPDTD-----TNHIVEASDYI----CMDT 74

  Fly   225 SISYSHLPATNGPYRPMPAEYGTYSYLPPQRYVRNLAEGAIVMLYHPCAFPGQVKQLQDIVGGCL 289
            .|.|:....|:|.|||:.||.|.|.|.||||::.||..|.:|.|||||......:.|..:...||
Zfish    75 PIKYNESLPTHGDYRPVEAESGEYIYCPPQRWLNNLKNGGLVFLYHPCVSAEARRSLAVLAHSCL 139

  Fly   290 YRHLVSPSLALSPQRPLALLAWSRSLEMS-----VVDRQLAA----------------DFIQKHA 333
            ..::::|...||..||||:::|.||||||     |.|..|:.                .::.|.|
Zfish   140 SHYILTPHPWLSQHRPLAVVSWGRSLEMSQITLRVCDWLLSIFPNITLFSTSHGVKYNMYLTKPA 204

  Fly   334 KQGPL-APEELSR--------------LIVKRQTYKEGLLREAHLVNTADDYEL 372
            ...|: ..:|:||              |.:||.|.|..:.    |..:.:|.||
Zfish   205 LHKPVNTSQEMSRVERLKSLKHCCMRILSLKRITRKTRMA----LKQSPEDAEL 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12093	NP_647747.1	DUF3105	223..341	CDD:288196	48/139 (35%)
tp53i13	XP_001338803.3	DUF3105	72..168	CDD:288196	40/95 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586688
Domainoid	1	1.000	94	1.000	Domainoid score	I7484
eggNOG	1	0.900	-	-		E1_2E13B
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0011880
OrthoInspector	1	1.000	-	-		oto41072
orthoMCL	1	0.900	-	-		OOG6_110757
Panther	1	1.100	-	-	LDO	PTHR34179
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7425
SonicParanoid	1	1.000	-	-		X5497
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.770