Protein Alignment AhcyL1 and Ahcy

DIOPT Version :10

• Sequence 1: NP_647746.1
• Gene: AhcyL1 / 38342
• FlyBaseID: FBgn0035371
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_057870.3
• Gene: Ahcy / 269378
• MGIID: 87968
• Length: 432
• Species: Mus musculus
• Alignment Length: 426
• Identity: 221/426 - (51%)
• Similarity: 306/426 - (71%)
• Gaps: 3/426 - (0%)

  Fly    97 VRNIGAQHAFGRREIEIAEQEMPGIIALKKRAAEDKPLKDAKIVGCTHINAQTAVLIETLVELGA 161
            |.:||.. |:||:.::|||.||||::.:::..:..||||.|:|.||.|:..:|||||||||.|||
Mouse     9 VADIGLA-AWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGA 72

  Fly   162 SVRWAACNIYSTQNEVAAALAESGIPIFAWRGETEEDFWWCIDRCVNAENWQPNMILDDGGDATH 226
            .|||::|||:|||:..|||:|::|||:|||:|||:|::.|||::.::.::...|||||||||.|:
Mouse    73 EVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTN 137

  Fly   227 LMLKKYPTMFKLVKGIVEESVTGVHRLYQLSKAGKLTVPAMNVNDSVTKTKFDNLYSCKESILDS 291
            |:..|||.:...::||.||:.||||.||::...|.|.|||:||||||||:||||||.|:||::|.
Mouse   138 LIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDG 202

  Fly   292 LKRSTDVMFGGKQVVVCGYGDVGKGCAQALKGQGCIVYITEIDPICALQASMDGFRVVKLNEVIR 356
            :||:||||..||..||.|||||||||||||:|.|..|.|||||||.||||:|:|:.|..::|..:
Mouse   203 IKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACK 267

  Fly   357 NVDIVVTATGNKNVVVREHMDKMKSGCIVCNMGHSNTEIDVNGLRTPDLTWEKVRSQVDHIIWPE 421
            ..:|.||.||..::::..|.::||...||||:||.:.||||..|....:....::.|||......
Mouse   268 EGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKN 332

  Fly   422 GKYIILLAEGRLVNLSCS-SIPSFAVSITSATQALALIELFNAPPGRYKSDVYLLPKKMDEYVAS 485
            |:.||||||||||||.|: ..|||.:|.:...|.:|.|||: ..|.:|...|:.||||:||.||.
Mouse   333 GRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELW-THPDKYPVGVHFLPKKLDEAVAE 396

  Fly   486 LHLPTFDAHLTELSDEQAKYMGLNKAGPFKPNYYRY 521
            .||...:..||:|:::||:|:|:...|||||::|||
Mouse   397 AHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AhcyL1	NP_647746.1	AdoHcyase	96..520	CDD:214963	218/423 (52%)
Ahcy	NP_057870.3	AdoHcyase	8..431	CDD:214963	218/423 (52%)
		NAD binding. /evidence=ECO:0000250|UniProtKB:P10760	183..350		90/166 (54%)