DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Non2 and TRI1

DIOPT Version :9

Sequence 1:	NP_647745.1	Gene:	Non2 / 38341	FlyBaseID:	FBgn0035370	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_013960.1	Gene:	TRI1 / 855273	SGDID:	S000004846	Length:	226	Species:	Saccharomyces cerevisiae

Alignment Length:	232	Identity:	54/232 - (23%)
Similarity:	106/232 - (45%)	Gaps:	47/232 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IQAVLKDADLATISAKRVREQVEGKLNCSLLSRKKEFDKIVMEVINEQQDEEDEDDDEGKDPDAD 77
            :.|:|..::...||.||||:.::...:.:|.|::|..:::::|...:.|:          :|...
Yeast    11 VDAILSVSNPDEISPKRVRKALQILYSVNLDSQRKLINELILERFGDIQE----------NPRVL 65

  Fly    78 PDDESEPSEEEDPSSSEEEAAKKKKQSPKKRPQPTKHKAPKKKRKTLNADDSGTESDAGSDSDYE 142
            .......|.:::.|...::..::..:|.:||...::.|:.:||:|    :||   .|:.|.|..:
Yeast    66 IPKNDLISRDQELSLRLQKEEERPLRSTRKRKGKSESKSKRKKKK----NDS---PDSNSISVRK 123

  Fly   143 VVKKPAAKKKAKAAGGTGSGRKSTGFTRAYNLSPELSALMGESSLPRHEVVKKVWAIIKERDLYD 207
            |:                             ||..|...:|...|||.:|||.:|..|||.||.:
Yeast   124 VL-----------------------------LSAPLQKFLGSEELPRTQVVKMIWQYIKEHDLQN 159

  Fly   208 PKNKQFAICDDELMKVMKIRRFRTFGMLKHLKPHFLD 244
            ||:::..:||:::..:.. ::...|.|.|.|..|..:
Yeast   160 PKDRREILCDEKMEPIFG-KKMTMFSMNKLLTKHLFN 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Non2	NP_647745.1	DEK_C	7..57	CDD:285919	12/43 (28%)
Non2	NP_647745.1	SWIB	170..242	CDD:280380	24/71 (34%)
TRI1	NP_013960.1	Rsc6	1..226	CDD:227818	54/232 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344412
Domainoid	1	1.000	52	1.000	Domainoid score	I2840
eggNOG	1	0.900	-	-		E1_COG5531
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I1758
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53067
OrthoFinder	1	1.000	-	-		FOG0002185
OrthoInspector	1	1.000	-	-		otm46913
orthoMCL	1	0.900	-	-		OOG6_104393
Panther	1	1.100	-	-	LDO	PTHR13844
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1401
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.790