Protein Alignment Non2 and Non2

DIOPT Version :10

• Sequence 1: NP_647745.1
• Gene: Non2 / 38341
• FlyBaseID: FBgn0035370
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_001237540.3
• Gene: Non2 / 4577435
• VectorBaseID: AGAMI1_003652
• Length: 289
• Species: Anopheles gambiae
• Alignment Length: 282
• Identity: 131/282 - (46%)
• Similarity: 169/282 - (59%)
• Gaps: 46/282 - (16%)

  Fly     8 DLRREIQAVLKDADLATISAKRVREQVEGKLNCSLLSRKKEFDKIVMEVINEQQDEEDEDDDEGK 72
            :|:.|||.:||||:|...:||:||.|:|..|.|.|.:||||.|::||:.:|.|...|.|:||:.:
Mosquito     9 ELKAEIQKILKDANLEETAAKKVRLQLEKNLKCDLSNRKKEVDELVMDYVNSQASSEGEEDDDEE 73

  Fly    73 DPD-----------------ADPDDESEPSEEEDPSSSE---EEAAKKKKQSPKKRPQPTKHKAP 117
            |.|                 :|.:|:.|..||||....|   ||...|.::|..||..|.|....
Mosquito    74 DDDHAGNGKGNKKDKKAKGNSDYEDDEEDEEEEDDDDDEDFSEEEKPKGRKSAGKRGTPAKRGPA 138

  Fly   118 KKKRKTLNADDSGTESDAGSDSDYE-------------------------VVKKPAAKKKAKAAG 157
            ||||:..|::|...:.|.|||.||.                         ...|||||.| ||||
Mosquito   139 KKKRRASNSEDDSGDDDKGSDDDYNPKGSGKGKAASKKKNNSDSDSDGDWKQTKPAAKAK-KAAG 202

  Fly   158 GTGSGRKSTGFTRAYNLSPELSALMGESSLPRHEVVKKVWAIIKERDLYDPKNKQFAICDDELMK 222
            |.|..::|.|:||.|.|||||:.:.|..||||||||||:|||||||:||||||:||||||::|.|
Mosquito   203 GGGGAKRSNGYTRPYTLSPELAEVCGAESLPRHEVVKKMWAIIKERNLYDPKNRQFAICDEQLRK 267

  Fly   223 VMKIRRFRTFGMLKHLKPHFLD 244
            |:.::|||||||||:|||||.|
Mosquito   268 VIGVKRFRTFGMLKYLKPHFKD 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Non2	NP_647745.1	DEK_C	5..57	CDD:462592	25/48 (52%)
		SWIB-MDM2_like	172..242	CDD:349489	51/69 (74%)
Non2	XP_001237540.3	DEK_C	5..57	CDD:462592	25/47 (53%)
		SWIB-MDM2_like	217..287	CDD:349489	20/29 (69%)