Protein Alignment Mrtf and mrtfaa

DIOPT Version :9

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_009297675.2
• Gene: mrtfaa / 797480
• ZFINID: ZDB-GENE-121205-3
• Length: 1030
• Species: Danio rerio
• Alignment Length: 1374
• Identity: 312/1374 - (22%)
• Similarity: 468/1374 - (34%)
• Gaps: 531/1374 - (38%)

  Fly   320 ARQSPPKAIVDSSPLQ----------PAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIH 374
            |..|.|::...::.||          |.:.:.|..|::||..||...:||:|||:|.||:|.:.|
Zfish    20 ASASSPQSEAVTNELQDLSLQPAPNLPPIYERKNVLQLKLQQRRTREELVDQGIMPPLKSSASFH 84

  Fly   375 EQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQI 439
            ||.:.||||:|.|.||.||:.||.|.:|.|:|||||...  :|||..||.:||:|||||.||.:|
Zfish    85 EQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSA--EPSLQAKQLLLKRARLADDLNDKI 147

  Fly   440 QHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDSLSSESDTRQ 504
            ..||||:||:.||||    |:...:|:.::           ..:.|.  |..::.|...||....
Zfish   148 SQRPGPMELVHKNIL----PVHSSIKQAII-----------ETEFPK--VEAENSSFDEESSDAF 195

  Fly   505 TPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPV 569
            :|.:     .|...||.....              :||:.:|             |.....|...
Zfish   196 SPEQ-----TAIQDSPLGHTH--------------LPTSAEL-------------PANEATPKQA 228

  Fly   570 PPPPPP--PPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSI 632
            ||||||  |.|.|.              ::|....||...:|        :|..|.
Zfish   229 PPPPPPALPSPTPQ--------------QKLLNGTTGQKQAP--------ALQKSG--------- 262

  Fly   633 ASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQ 697
                              .|.|:.|.: :::|...:||  |.:.:|:|:|. ||.   ||.::..
Zfish   263 ------------------KVSSERPAQ-RSKKVRDNKP--KVKKLKYHQYV-PPD---QKAEREP 302

  Fly   698 PE--ETSYQLMLEQQNCLLKFLENLNKNQ------SIIPAPSAPGVMLPAAPGATNNSITVTTKT 754
            |.  ::||..:|.||...|: |:.:|:.|      :|:|||..|    ||             ..
Zfish   303 PPLLDSSYAKLLYQQQLFLQ-LQIINQQQQNYNYHTILPAPPKP----PA-------------DQ 349

  Fly   755 VPALA---SQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQ 816
            .||.|   |||.....|.|  .:.::||.:..:.:|.|...:       :|.||
Zfish   350 QPASASGQSQSKNDTPPQS--TSTNLTSQNQQSTINVGRVNI-------SPLPP----------- 394

  Fly   817 LQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQ 881
                                                                 .||::||::|||
Zfish   395 -----------------------------------------------------NLEELKVAELKQ 406

  Fly   882 HLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAPTSNNSNTTPEVI---------------- 930
            .||.|.|.|||.|..|||||:.:  .|.......|.|.:|    ||..:
Zfish   407 ELKLRGLTVSGTKNDLIERLRNF--QEQNGGTSPPTPKTN----TPSALGGGASSTHQSTDRNLM 465

  Fly   931 --------------TISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDN-----THP 976
                          |::.|......|.....|||:...|:.|......|......|.     :.|
Zfish   466 VASFQFGATAEGGGTLTTAPMMMQFGSTSSSPPVSPAHSERSSTGMSPDEASCHADAFGEMVSSP 530

  Fly   977 MTLQTILPPQPQTATIILTNE--------------------ELLREQQRKIDELQRQLQRSQQEL 1021
            :|..::.|..|...|:.:..|                    ::|.|:.|:|.||...|.:.||.:
Zfish   531 LTQLSLQPSPPLPTTVCIKEEPCSQTYQSSSCMLSRSADKDQMLLEKDRRIQELTNMLLQKQQLV 595

  Fly  1022 QKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKAT 1086
            :.:|.:.:.::.|:...|.    .|||:..|..:                        :||||
Zfish   596 ESLRLQLEGKRVQEPNPVK----EALPAAVIEAL------------------------RVTVK-- 630

  Fly  1087 GGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAA 1151
                 .:|..:.:                           :.:||.:.|:|.
Zfish   631 -----EEVMEVVE---------------------------DSEMVTEPQVEL------------- 650

  Fly  1152 QQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKKSN 1216
               :|||:...:|.|:..|||..|::::       |||.|..|
Zfish   651 ---EQQQRIVMRQNQRNLLQQTHQRKRK-------TQKQQRQF---------------------- 683

  Fly  1217 VPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGN 1281
             |...||       |.:.|  |::...||.|.  |:...:..:||....||.|::||..|...|.
Zfish   684 -PQALTN-------QQSSP--VSSVPVSPVNP--NSTPTIVTDGNGNQFLLTLSNQHTEAPARGR 736

  Fly  1282 ISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQ 1346
                                    .|..|..| ..|...|.|      |.:.:..|...:|....
Zfish   737 ------------------------RPQGKATN-QSRLQRLQS------TSTTLPNQSEAELLNNN 770

  Fly  1347 QQQQQFQPV--QQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQS 1409
            .|.:..|.|  :||.::.|.           |....||...|:|.:.........|....:....
Zfish   771 NQPEPIQTVILKQPIKKALK-----------PDLNVATNYKASSSSFVSTSFFSSVDSMNDGDVV 824

  Fly  1410 PAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPES---------AALEPITPLT--- 1462
            |         ::|.......|...:.|.|:.||||::||:.|:         ..|.|.||||
Zfish   825 P---------SSPNNNNNIGSGSHQHVDDLFDILIQRGEISENFKASPDPVLERLRPNTPLTLSF 880

  Fly  1463 -PLPELSMFNGAT---------------PTTAAGGAS-------------------------IVP 1486
             || .||..:..|               ||:.|.||.                         ||.
Zfish   881 SPL-NLSPASENTIKTLIAEPRPPSIKVPTSCATGAGRLEDFLESTTGKPLLGVEPGGPTTLIVD 944

  Fly  1487 L------VPK-LETPVTPVQNLDV----------------AMDTNVQHVGFASNQAPNHVFIESI 1528
            |      .|. |:.|..|:...|:                :||.....||.::.:.|..|.|...
Zfish   945 LHNQMLSTPSILDHPRCPMDTYDISFSSHSASDLVDSAPDSMDWMELGVGASAGEVPGLVHINGH 1009

  Fly  1529 DMASPLQTD 1537
            :.:|....|
Zfish  1010 NPSSLFSAD 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	15/24 (63%)
		RPEL	433..458	CDD:128947	14/24 (58%)
		SAP	871..905	CDD:280251	20/33 (61%)
mrtfaa	XP_009297675.2	RPEL	54..78	CDD:128947	11/23 (48%)
		RPEL	97..122	CDD:128947	15/24 (63%)
		RPEL	143..163	CDD:308408	13/23 (57%)
		SAP	396..429	CDD:307935	20/32 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580437
Domainoid	1	1.000	46	1.000	Domainoid score	I12103
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3905
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001082
OrthoInspector	1	1.000	-	-		otm24647
orthoMCL	1	0.900	-	-		OOG6_104701
Panther	1	1.100	-	-	O	PTHR22793
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2343
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.890