Protein Alignment Mrtf and mrtfa

DIOPT Version :10

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: NP_001072754.1
• Gene: mrtfa / 780211
• XenbaseID: XB-GENE-486827
• Length: 1033
• Species: Xenopus tropicalis
• Alignment Length: 1347
• Identity: 300/1347 - (22%)
• Similarity: 469/1347 - (34%)
• Gaps: 533/1347 - (39%)

  Fly   333 PLQPAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRP 397
            |..|.:.:.|..|::||..||...:||.|||:|.||:..|.|||.:.||||:|.|.||.||:.||
 Frog    88 PNSPPLSERKNVLQLKLQQRRTREELVNQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRP 152

  Fly   398 NREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEK 462
            .|.:|.|:|||||...  :|||..||..||:|||||.||.:|..||||:||:.||||    |:|.
 Frog   153 ERAELVRMHILEETSA--EPSLQAKQMKLKRARLADDLNEKISQRPGPMELVVKNIL----PVET 211

  Fly   463 IVKEGLVSFKATSEGLLTRPQHPH--SYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQ 525
            .:||.::..           .:|.  ...:||:||                         :|.|
 Frog   212 SLKEAIIDV-----------DYPKVVDNSSFDEDS-------------------------SDAL- 239

  Fly   526 AAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQE 590
                                    ||: .|..|:.:. .:|:|:...|....|:|:.|
 Frog   240 ------------------------SPE-QPASQESQG-SIPSPLEMRPSETTPIPLLS------- 271

  Fly   591 TANLYEELCQSVTGTTASPVNHL----YSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVS 651
                   .||    ..|.|...|    ::..||.|:|.|:|          ..:|.:.....|..
 Frog   272 -------PCQ----LQAFPCVQLGTDPFNQDSLQSTTITIS----------NGLTASICKSLPAL 315

  Fly   652 VKSDAP----GKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNC 712
            ||...|    .|.:..||.| :|..|.:.:|:|:|. ||.   |||..|...::||..:|:||..
 Frog   316 VKQSQPKPSIEKSQRTKKPK-EPKPKVKKLKYHQYI-PPD---QKQKGTPAMDSSYAKLLQQQQL 375

  Fly   713 LLKFLENLNKN-------QSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPIS 770
            .|: |:.:|:.       |:|:|||..|   ||.... ||.|.:.|.:::|.:
 Frog   376 FLQ-LQIINQQQHQHYNYQTILPAPPKP---LPDQQN-TNGSSSTTVRSMPTV------------ 423

  Fly   771 LPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHP 835
                              |.:|:.|||                     :.:|:..
 Frog   424 ------------------GPSTLATPT---------------------ITRQNSN---------- 439

  Fly   836 PPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIER 900
                   ::|.....|.|               ..|::|||::|||.||.|.|||||.|..||||
 Frog   440 -------VAVGGRTGPLP---------------HNLDEMKVAELKQELKHRGLPVSGTKIDLIER 482

  Fly   901 LKPYLPLEPLDSNVTPA--PTSNNSNTTPEVI------TISDAMDTSNCGLLEQPP--------- 948
            ||  ...:|....|.|.  ||.......|||:      .::....|..|.....||
 Frog   483 LK--ASQDPNTVTVPPVAKPTPVQPAKPPEVMPTLSISCLNTTESTKLCSTSSTPPGSPCPSEVS 545

  Fly   949 PVTM----LVSDASMEHEQMDVVQQQMDNTH-PMTLQTILPPQPQTATIILTNEELLREQQRKID 1008
            .|:|    ::|||..|.....|.||.:.|:. |:|.::...|:.:        :.:|||:.::|:
 Frog   546 VVSMDEVSIISDALGETIACPVTQQVLQNSSAPVTEKSSSDPRDK--------DLMLREKDKQIE 602

  Fly  1009 ELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQV 1073
            ||.|:|::.|:.::::||:.:|::..||.       ::...||..::..
 Frog   603 ELTRRLKQKQELVERLRQQLEQEKRTQQH-------HSADDQQALILAV---------------- 644

  Fly  1074 EKNFPAKVTVKATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEA 1138
             |..|..:|:.:        :|.        ||..|..||:                 ||::|..
 Frog   645 -KQEPVSLTIDS--------INN--------KKETSEASNN-----------------VKKELNR 675

  Fly  1139 KIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLL--------------TQK 1189
            .|         |.||:.|                            ||              :..
 Frog   676 VI---------ACQQETQ----------------------------LLIGSMSGGIEGKVDGSGG 703

  Fly  1190 TQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLG 1254
            |:.||              ...:..|.:|..|            :...:......|.:.|..|
 Frog   704 TKLVF--------------TLASPSSQLPEEN------------RQIVLQRVPTPPSSLHPTN-- 740

  Fly  1255 LLWNEGNQTILL--LGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQR 1317
               :...|.:||  ..|.:|...      :.|...|..:.:|....|:..         :||.|:
 Frog   741 ---SLPKQEVLLNHCALQNQKPA------LQLMPGTVLSLSPSNLQPILN---------MNGFQK 787

  Fly  1318 TNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAP-------- 1374
            .        |.:|.:       ..:|:|:....: .|...|.|.:       |.|.|
 Frog   788 R--------PADTSN-------SSIQKQKPVHNE-SPATPPPQPE-------PEPPPHSIFLTAS 829

  Fly  1375 -------PPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIK 1432
                   ||.||||.||..:|......|.|
 Frog   830 SPPWSKDPPGYEEAVKQQPSSSEDGRPGGL----------------------------------- 859

  Fly  1433 SEQVSDVLDILIKQGELPES------AALEPITPLTP----LPELSMFNGATPTTAA-------- 1479
              |..:..|:||:..:||..      ..|:..:|..|    :|::.|....:|..:|
 Frog   860 --QAEEFFDLLIQNLDLPSEFKDYLVPCLKQTSPSHPAVQTVPQVEMPPPPSPIQSALGRLEDFL 922

  Fly  1480 -------------GGASIVPLVPKLET-----------PVTPVQNLDVAMDTNVQHVGFASNQAP 1520
                         .|.:.:||:..|.:           |.:|:...|:........:|...::.|
 Frog   923 ESSTGSPLLRGNQDGPAFMPLIDDLHSQMLSSLAILDHPPSPMDTSDLHFSPVGDSLGLDISEPP 987

  Fly  1521 NHVFIESIDM----------ASPLQTDSSAIDAESVAKTLDIFLEQH 1557
                ::.:|.          .:||.|.:.::.:..       ||:.|
 Frog   988 ----LDGMDWLELSEPPAMNLTPLSTATPSVFSTD-------FLDSH 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	15/24 (63%)
		RPEL	433..458	CDD:128947	14/24 (58%)
		SAP	871..905	CDD:460424	22/33 (67%)
mrtfa	NP_001072754.1	RPEL	99..123	CDD:128947	11/23 (48%)
		RPEL	142..167	CDD:128947	15/24 (63%)
		RPEL	186..210	CDD:128947	15/27 (56%)
		SAP	453..484	CDD:460424	20/30 (67%)
		cdk7	<589..>666	CDD:129661	23/124 (19%)