Protein Alignment Mrtf and Mrtf

DIOPT Version :10

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_061502900.1
• Gene: Mrtf / 5667575
• VectorBaseID: AGAMI1_006042
• Length: 1283
• Species: Anopheles gambiae
• Alignment Length: 1384
• Identity: 360/1384 - (26%)
• Similarity: 515/1384 - (37%)
• Gaps: 465/1384 - (33%)

  Fly   284 IILLHEAYDDMSEG-EQRL--HATFLGSSDDGNNSDCYDARQSPPKAIVDSSPLQPAMDKNKESL 345
            :.|..|...||... ..||  |...|   |:|.......:|.|||||::||||||.||||||:||
Mosquito     6 LFLPDEVVVDMDPNMTNRLQQHTVVL---DEGAQPGTSYSRVSPPKAVIDSSPLQSAMDKNKQSL 67

  Fly   346 KVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEE 410
            .|||.:|||:.|||:|||:|||||||||:||.:|||||||.|||||||::||:|.:||:.||||:
Mosquito    68 IVKLSMRRPYDQLVQQGIMPSLKTSPAIYEQRRQLERAKTGDLLKAKIKKRPDRLELEQRHILEQ 132

  Fly   411 DECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKAT- 474
            .:.|:|||||||:|||:||.|.|.|||:|.||||||:||.|||||.|:|||::||||||.:.:|
Mosquito   133 CDSHVDPSLAEKRRMLEKALLVDHLNSKISHRPGPLDLIGKNILHVEEPIERMVKEGLVDYASTL 197

  Fly   475 --SEGLLTRPQHPHSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSP----TDVLQAAAASAGI 533
              |...:..|    :.|...:||||||.::      |....||..:.|    |.:||   ....:
Mosquito   198 DESNASVATP----TTVGEGEDSLSSEGES------LHSVTVAVVNQPGVPATTILQ---HQIQL 249

  Fly   534 VTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVP-------------PPPPPPPPLPMASII 585
            .......|||...:.:.||.| ...||:...:...:|             .|........:|:|.
Mosquito   250 QPFPAATPTAATSLQSQPQTL-LTAQPEFFTLKPTIPIVVNDGTVLAAIATPTVMAATTAVATIA 313

  Fly   586 KVKQE-----TANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASP--PPP----- 638
            .|...     .|.:..|......|..|:|.:   |...:.||::|.|..:|...|  |.|
Mosquito   314 AVTSSGNIATIAEIPMEQGGGGGGVAATPSS---SSTIITSSSNTPSITTSTLRPILPTPSANNN 375

  Fly   639 ---PMTTTRLHLAPVSVKSDAP------------------GKDK-NRKKSKSKPVSKARTIKFHE 681
               .:.|.|..|....:.||..                  ||:| .:||||:|.::||:.|||||
Mosquito   376 LSGDLATVRPTLTMTPIPSDLKLISSSSSSNGSGIAGSNGGKEKLAKKKSKTKSITKAKPIKFHE 440

  Fly   682 YKGPPSA-AGQKQDQTQP------------EETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAP 733
            |||||:| .|.....:..            .:.:|||:::|| .||::||.:.|..:.:.:||:.
Mosquito   441 YKGPPNAHRGSSSSSSSSAGHGGGGSGGGGSDNNYQLIMQQQ-YLLEYLEEMCKKPAGVSSPSSS 504

  Fly   734 GVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTP 798
                ..||..||      |.......|...|..:|:. |.. |.:...|||....|.......|.
Mosquito   505 ----REAPTTTN------TDAEELAGSDQTPIDSPLG-PGG-SSSGVGGGAGSGSGPGRSKNSTT 557

  Fly   799 AATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTS 863
            ....|....|:                                .:..|:::|          ||.
Mosquito   558 GGGGTGSGSSV--------------------------------GMGTSTTLP----------TTF 580

  Fly   864 SITDLA--RLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYL-PLEPLDSNVTPAPTSNNSNT 925
            :..|:|  .|.::|||.||::.|:.||.|||.|.:||||||||: .:||....|........:..
Mosquito   581 AAMDIALDTLNRLKVSQLKKYCKQYNLAVSGTKSNLIERLKPYIKSIEPCAGGVPSTVGGATAGG 645

  Fly   926 TPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDN-----THPMTLQ---TI 982
            |.|. .|.|::      |.||...:..|........|:::..:...:|     ..||.:.   ||
Mosquito   646 TAEA-EIEDSL------LAEQQKRIAELQLQLKKSQEELEQFRSLCNNPFAASDQPMVINAAVTI 703

  Fly   983 LPP--------------QPQTATIILTN------------------------------------- 996
            .||              |||.||:::.:
Mosquito   704 PPPPPPPPSSSSSSSAHQPQLATVLVGSPYSLTTGGGGDSCDAPCTADGDASAGGTVSANQTPDR 768

  Fly   997 ------------------EELLREQQRKID-----------ELQRQL---QRS---QQELQKIRQ 1026
                              |.|.......:|           ||...|   :||   :..|.|:
Mosquito   769 VSVPDTTVGAALEGSFFLEGLTPADSTTVDYGHDMHEMLPPELTSTLAPIERSPTHRPTLDKV-- 831

  Fly  1027 RQQQQQHQQQQTVTAQVVNALPSQQI--------------------------------------- 1052
                 ..|.|.|::...:...|:.::
Mosquito   832 -----LGQVQPTISGLTMKTEPTDELRNGGAGGGMSSVVGAGVAGGNGNAGGVRAAVGDMHDLSL 891

  Fly  1053 --------TLITTTSNGPQQTLTVMPQQVEK----NF---------------------------- 1077
                    .:...|.:|..|..|:|....|.    :|
Mosquito   892 SMKSVNFEAVNGDTGDGSMQQDTIMLNDFEDIDLVDFHMHSLDSDGPFPMITNHDPDPAATRTAA 956

  Fly  1078 ---PAKVTVK-------------------ATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISS 1120
               ||..|:.                   ||...:.::..|.|||....:...|....:|:::.|
Mosquito   957 HAPPAAATMHDAIDAMFCNGDGDPNGKLLATNSFATNQPTGSQQQHVLHEHAPSHGFLNNNDLVS 1021

  Fly  1121 SNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRL 1185
            .|    :.::::...|..:.::|...|.....:|........||.|...||...|||||||.
Mosquito  1022 GN----SLRIMLHMDLMDQNEQQANIATVTGTKQLPFGSLHHQQPQHHHLQHNNQQQQQQQH--- 1079

  Fly  1186 LTQKTQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAA-------AA 1243
                        ::.:|::::.   ....|...||.|.:....:.|..:|.|..:|       ::
Mosquito  1080 ------------HHTSHLHHSD---RNNNSRYDANQTVSLGFGVQQDTQPVASTSASSSSSSTSS 1129

  Fly  1244 SPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPP 1308
            ||.|.....||            ..|:.:|...|.
Mosquito  1130 SPSNCFRLGLG------------TSLSSKHANKHH------------------------------ 1152

  Fly  1309 KKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPA 1373
               ||.||                   |||..|.|||.|||||..|.....||
Mosquito  1153 ---LNLHQ-------------------QQQQHQHQQQHQQQQQHHPHHHHHQQ------------ 1183

  Fly  1374 PPPQYEEATKQLAASKAAA 1392
               .::...:||....|||
Mosquito  1184 ---HHQSLLEQLTPPSAAA 1199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	16/24 (67%)
		RPEL	433..458	CDD:128947	18/24 (75%)
		SAP	871..905	CDD:460424	20/33 (61%)
Mrtf	XP_061502900.1	None