Protein Alignment Mrtf and mrtfab

DIOPT Version :9

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_021335791.1
• Gene: mrtfab / 559638
• ZFINID: ZDB-GENE-030131-681
• Length: 1217
• Species: Danio rerio
• Alignment Length: 1501
• Identity: 365/1501 - (24%)
• Similarity: 556/1501 - (37%)
• Gaps: 499/1501 - (33%)

  Fly   330 DSSPLQPAMDKN-----KESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLL 389
            |..|:....|::     ||.|::||..||...:||.|||:|.||:..|.|||.|.||||:|.|.|
Zfish    25 DKMPVSLDCDRHAYHNLKEVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRKSLERARTEDYL 89

  Fly   390 KAKIQQRPNREDLERLHILE-------EDEC------HIDPSLAEKQRMLKKARLADQLNSQIQH 441
            |.||:.||.|.:|.|:||||       ...|      ..:|||..||..||:|||||.||.:|.|
Zfish    90 KRKIRSRPERSELVRMHILEVTTETASSSVCKTNIKTSAEPSLQAKQLKLKRARLADDLNDKISH 154

  Fly   442 RPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDS---LSSESDTR 503
            ||||:|||.||||    |:..::  |..|.|..|..|             |:||   ||.:....
Zfish   155 RPGPIELIHKNIL----PVHALI--GTESPKGESSSL-------------DEDSSDALSPDPQCS 200

  Fly   504 QTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSP-QILPQQQQPKAIVVPA 567
            |..|    ..:....||:|:|.                ..|.|   || |.|.|
Zfish   201 QDSP----LGLGPQHSPSDMLN----------------MNGDL---SPSQFLTQ----------- 231

  Fly   568 PVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSI 632
                   .||||.:.|                      .|||..:|.|..::::|:.
Zfish   232 -------APPPLLVTS----------------------DASPPKNLTSETNISNSSR-------- 259

  Fly   633 ASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSK-SKPVSKARTIKFHEYKGPPSAAGQKQDQT 696
                 ||...|:.       ||......:..||.| :||  |.:.:|:|:|. ||.   ||.|:.
Zfish   260 -----PPSGHTKF-------KSSTDRTYQRSKKPKDNKP--KVKKLKYHQYI-PPD---QKNDRE 306

  Fly   697 QPE--ETSYQLMLEQQNCLLKFLENLNKNQ------SIIPAPSAPGVMLPAAPGATNNSITVTTK 753
            .|.  ::||..:|.||...|: |:.:|:.|      :|:|||
Zfish   307 PPPQLDSSYAKILHQQQLFLQ-LQIINQQQQHYNYHTILPAP----------------------- 347

  Fly   754 TVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQ 818
              |.||::       :..|:|                    .|.||.:.|..|.:.:::.|....
Zfish   348 --PKLATE-------MQQPST--------------------NPGPAPSQTISTSTAVSSNQTGTS 383

  Fly   819 LHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHL 883
            ...|                |:.|.:..|::|                  |.|::.||::||..|
Zfish   384 RQSQ----------------PTVAGAKPSTLP------------------ANLDEFKVAELKHEL 414

  Fly   884 KRRNLPVSGPKPHLIERLKPY---------------------LP---------LEPLDSNV---- 914
            |.|.|.|||.|..||||||.|                     ||         ..|.|:.|
Zfish   415 KLRGLTVSGTKNDLIERLKNYQEQNCGSSAAGAPAMKTVPAQLPQVSIQSGPHQHPKDTTVPISA 479

  Fly   915 ---TPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMD---- 972
               ||. |..:|.|.|:::..|....:         |||:...||.|:.....|......|
Zfish   480 FPLTPT-TRVHSTTPPQIMRFSSTSSS---------PPVSPTPSDRSVTGLSPDEASCNGDVFGE 534

  Fly   973 -NTHPMTLQTILPPQPQTATII---------------------------------LTNEELLREQ 1003
             .:.|:| |..|.|.|:..:.|                                 |..:::|:|:
Zfish   535 MVSSPLT-QLSLHPSPEQPSPIKEESLGQVQSSCSLSRLGTLPAAQPHDPCPLSPLDKDQMLQEK 598

  Fly  1004 QRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQI--TLITTTSNG----- 1061
            .::|:||.|.|::.|::::.:|.:.:|.:            .|.|::..  |.|...|||
Zfish   599 DKQIEELTRMLRQKQRQVEALRSQLEQGK------------RAAPTEPAVDTEIPMLSNGVEVKV 651

  Fly  1062 ----------------------------PQQT---------LTVMPQQVEKNFPAKVTVKATGGN 1089
                                        .|||         |.|..||:..:.|   .::.|
Zfish   652 KEEVKEEMDTSEDLQKQIQPLKKIQTQCSQQTLFKLQQIHRLQVQQQQILVDLP---NLQNT--- 710

  Fly  1090 SNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPI---NQKMVVKQQLEAKIQKQKAAAAAAA 1151
            ...:|:.|:.|...||          :.:|......:   :||:.:.||.:|::.:|:..|....
Zfish   711 QQQEVDQLKVQQEQAK----------TQVSQQQKTQLLQHHQKVQLLQQQKAQLLQQQQKAQLLQ 765

  Fly  1152 QQQQQQQ--QQQQ----QQQQQQALQQQQ-----QQQQQQQQVRLLTQKTQTVFIPFNNNNHINN 1205
            ||||:.|  ||||    |:||:..|.||:     ||||||:..:|:.|::|...:..|.......
Zfish   766 QQQQKAQLLQQQQRTLVQEQQKTQLHQQKKATLLQQQQQQKLQQLIIQQSQQKQLQANLKQQQKP 830

  Fly  1206 ASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASP-------GNQHHNNLGLLWNEGNQT 1263
            .:...:.:.|.|..:..::|..|   .:.|..:..|..:|       ||::     |:....|..
Zfish   831 QNLLQSPQVSQVFVSQQSSTQIT---TSFPLDILKAHPTPTLVTDSNGNRY-----LIALTSNSV 887

  Fly  1264 ILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPI 1328
            ..|.|.:.|   :.:.|.|:|....:|....|:.:....:|.|            |...::..||
Zfish   888 ESLTGKSPQ---SKSNGRITLQRLQSTPIKLPSQSSTDMTTSA------------NHSQAVREPI 937

  Fly  1329 ETKS--IITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAA 1391
            ..|:  .:....:|:..|.......|:|....:...||:      |..||.::|
Zfish   938 TKKAGLHVETSSVQESSQPVSAPPSFEPFFCEESNPLNK------PTSPPSFKE----------- 985

  Fly  1392 ALNGLLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPE--SAA 1454
               .:.|  ......:.:|: |..|.|| .|.|.:...| .::|:.|:.:||:|.||:..  .|:
Zfish   986 ---DICP--TFDRHTLFTPS-SPKPNPQ-PPQCLKDNVS-NNQQIDDLFEILMKSGEISSGFKAS 1042

  Fly  1455 LEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLETPVTPVQNLDVAMDTNVQHVGFASNQA 1519
            .:|     .|.:|.. |..:|:.......:.|.....|....|.|.|   :||..:.   .|:..
Zfish  1043 QDP-----SLSDLHS-NPPSPSPPPSPLHLSPPAHHPEPMPVPSQQL---LDTQNRP---CSSTG 1095

  Fly  1520 PNHVFIESIDMASPLQTDSSAIDAESVAKTLDIFLEQHHATP-----PPSTPPKSCHSGSEKPNS 1579
            ....|:||...|..|     .::.:|....:|....|..:|.     |||....|..|.|..|.|
Zfish  1096 RLEDFLESTTGAPLL-----GVEPDSPLTLIDDLHSQMLSTSSILDHPPSPMDTSDLSFSSHPAS 1155

  Fly  1580 PDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSSNNNGNLRRDLNPSLQPSI--NELL 1642
            .|     |::..|           .|.|..|....:...:.|..|.:...|:....||:  .:.|
Zfish  1156 LD-----FEDPAL-----------DGMDWLGIPVVTGGSNCNGGGLVLAPLSSHTPPSVFSADFL 1204

  Fly  1643 DASSPD 1648
            |  |||
Zfish  1205 D--SPD 1208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	14/31 (45%)
		RPEL	433..458	CDD:128947	16/24 (67%)
		SAP	871..905	CDD:280251	20/54 (37%)
mrtfab	XP_021335791.1	RPEL	43..68	CDD:128947	12/24 (50%)
		RPEL	87..111	CDD:128947	14/23 (61%)
		RPEL	148..168	CDD:308408	15/23 (65%)
		PARP_reg	363..>439	CDD:332154	31/109 (28%)
		SAP	402..435	CDD:307935	19/32 (59%)
		DD_cGKI	593..625	CDD:327379	9/31 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580433
Domainoid	1	1.000	46	1.000	Domainoid score	I12103
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	187	1.000	Inparanoid score	I3905
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001082
OrthoInspector	1	1.000	-	-		otm24647
orthoMCL	1	0.900	-	-		OOG6_104701
Panther	1	1.100	-	-	LDO	PTHR22793
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2343
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.980