Protein Alignment Mrtf and Mrtfb

DIOPT Version :10

• Sequence 1: NP_001137879.3
• Gene: Mrtf / 38338
• FlyBaseID: FBgn0052296
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_006522171.1
• Gene: Mrtfb / 239719
• MGIID: 3050795
• Length: 1112
• Species: Mus musculus
• Alignment Length: 1493
• Identity: 344/1493 - (23%)
• Similarity: 529/1493 - (35%)
• Gaps: 556/1493 - (37%)

  Fly   268 LATRLSGKDLEHSFQDIILLHEAYDDMSEGEQRLHATFLGSSDDGNNSDCYDARQSPPKAIVDSS 332
            ||.....:.:.|.||::.|           :...|...|....:|:             .:...|
Mouse    19 LAPSPQSESVAHEFQELSL-----------QSSQHLPTLNERKNGS-------------IVFGES 59

  Fly   333 PLQPAMDKNKES--LKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQ 395
            .||..:.....|  |:::|..||...|||:|||:|.||:..|.|||.|.||||:|.:.||.||:.
Mouse    60 GLQLPLPAQSVSTVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRS 124

  Fly   396 RPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPI 460
            ||:|.:|.|:||||  |...:|||...|..||:|||||.||.:|..||||:||::||||    |:
Mouse   125 RPDRSELVRMHILE--ETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNIL----PV 183

  Fly   461 EKIVKEGLVSFKATSEGLLTRPQHPHSY--VTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDV 523
            :..|||.::.        :.:..:||::  .:||:||    ||.........:....:::||::.
Mouse   184 DSSVKEAIIG--------VVKEDYPHTHGEFSFDEDS----SDALSPDQPASQESQGSAASPSEP 236

  Fly   524 LQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVK 588
            ..:|:..      .:|..|..|....||.:      |:.:..|.....||
Mouse   237 KVSASPP------PVTASTPAQFTSVSPAV------PEFLKTPLTADQPP--------------- 274

  Fly   589 QETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVK 653
                                           ..||:.:.|.::::|....||...:.|  |.:
Mouse   275 -------------------------------TRSTAPVLPTNTVSSAKSGPMLVKQSH--PKN-- 304

  Fly   654 SDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPE-ETSYQLMLEQQNCLLKFL 717
                ..||:|.|....|..:.:.:|:|:|. ||:   ||.::::|: :::|..:|:||...|: |
Mouse   305 ----PNDKHRSKKCKDPKPRVKKLKYHQYI-PPN---QKGEKSEPQMDSNYARLLQQQQLFLQ-L 360

  Fly   718 ENLNKN-----------QSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISL 771
            :.|::.           |:|:|||                     .||
Mouse   361 QILSQQQQQQQQQHYNYQTILPAP---------------------IKT----------------- 387

  Fly   772 PNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPP 836
                ...||||.   |.|.::.:                                    |.:.|.
Mouse   388 ----DKNSSSGS---NSGSSSSM------------------------------------PARRPG 409

  Fly   837 PLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERL 901
            ||||                             .|:.:|||:||..||.|.|||||.||.|||||
Mouse   410 PLPS-----------------------------SLDDLKVSELKTELKLRGLPVSGTKPDLIERL 445

  Fly   902 KPYLPLEPLDSNVTPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTM-------------- 952
            |||..:           ||:|..|...|...|..:.|||..:....|..|:
Mouse   446 KPYQEV-----------TSSNLATGSIVAVSSATIVTSNPEVTVALPVTTLHNAVTSSVSTFKAD 499

  Fly   953 --LVSDASMEH---------------EQMDVVQQQMDNTHPMT-LQTILPP-------------- 985
              |.:.:|:.|               ||..:.....:.|...| :.|::.|
Mouse   500 LALPATSSVPHVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSH 564

  Fly   986 ----QPQTATIILTNEEL--------LREQQRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQT 1038
                .|.::|  |:..||        |:|::::|:||:|:|::.|:.::.::.:.:.::..||:.
Mouse   565 DDSLSPSSST--LSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQRP 627

  Fly  1039 VTAQVVNALPSQQITLITTTS-------------------NGPQQTLTVMPQQVEKNFPAKVTVK 1084
            ...|     ||.......|:.                   :.|||.:||
Mouse   628 PDPQ-----PSDPPHPFNTSDPKHGSVGSSIKDEASLPDCSSPQQPITV---------------- 671

  Fly  1085 ATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAA 1149
                           .|.:..:|.|:.|               |.:|.|:.:   :.||:...|.
Mouse   672 ---------------PGHSVGQPISTGS---------------QTLVAKKTV---VVKQEVPMAQ 703

  Fly  1150 AAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKK 1214
            |.||....|.....|.|..||..|.|        .|||.:|..:.:|
Mouse   704 AEQQNVVSQFYLSSQGQPPALVAQPQ--------ALLTTQTTQLLLP------------------ 742

  Fly  1215 SNVPANNTNTTTATM----MQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMT 1275
              |....:|.|:..:    :|...||. ....|.|                           |:.
Mouse   743 --VSIQGSNVTSVQLPVGSLQLQTPAQ-GRVQAQP---------------------------HVA 777

  Fly  1276 AHTLGNISLTATTTTTAAPPAATPVAASTIAP------PKKILNGHQR-----TNSLPSIVFPIE 1329
            |             .|..|.||.|.|.::..|      |:.:|...|.     |||.|:.|
Mouse   778 A-------------ATQVPAAALPSALTSALPQKQEAFPQHVLGQPQPVRKVFTNSAPNTV---- 825

  Fly  1330 TKSIITQQQLQQLQQQQQ----QQQQF-----QPVQQPKQQQLNQVD------IKPAPAPPPQYE 1379
                        ||.|:|    .||.|     .|..|.:...|..:.      .||:..||||..
Mouse   826 ------------LQYQRQPGPTNQQPFVSKTSNPALQSRTAPLAPLQNGPSLASKPSSPPPPQQF 878

  Fly  1380 EATKQLAASKAAALNGLLPLVKIKEEPVQSPAPSAAPLPQTA-PLCKRKTASIKSEQVSDVLDIL 1443
            .....|.|:         |:.|.|:.|....|...|...|.| |    :.:|:.|:|:.|:.|||
Mouse   879 VVQHSLFAT---------PITKTKDPPRYEEAIKQARSTQPALP----EVSSVHSQQMDDLFDIL 930

  Fly  1444 IKQGEL--PESAALEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLE--TPVT--PVQNLD 1502
            ||.||:  |......||:.:.|:.       |:.||......:....|:::  .||:  ||.:|.
Mouse   931 IKSGEISFPIKEEPSPISKMKPVT-------ASITTMPVNTVVSRPPPQVQIAPPVSLEPVNSLS 988

  Fly  1503 VAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAIDAESVAKTLDI---------FLEQHH 1558
            .:::..::  .|.....|      |.....|||..|.  |.||.:...|:         .|.|.|
Mouse   989 ASLENQLE--AFLDGTLP------SATDTGPLQNSSE--DRESFSLIEDLQNDLLSHSSMLYQSH 1043

  Fly  1559 ATPPPSTPPKSCHSGSEKP-NSPDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSS 1620
            :  |..|......||:  | .|.|...::.|..|.|::       .|...|||....|....|
Mouse  1044 S--PMETSEAQLVSGT--PCLSLDLSDSNLDNMEWLDI-------TMPTTSSGLTPLSTTAPS 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrtf	NP_001137879.3	RPEL	387..412	CDD:128947	13/24 (54%)
		RPEL	433..458	CDD:128947	14/24 (58%)
		SAP	871..905	CDD:460424	23/33 (70%)
Mrtfb	XP_006522171.1	RPEL	73..97	CDD:475195	11/23 (48%)
		RPEL	117..140	CDD:460677	13/24 (54%)
		RPEL	160..185	CDD:128947	15/28 (54%)
		PHA03247	<218..342	CDD:223021	32/193 (17%)
		SAP	415..448	CDD:460424	22/32 (69%)
		DUF2130	583..>618	CDD:430914	8/34 (24%)