Protein Alignment MEP-1 and pzf-1

DIOPT Version :10

• Sequence 1: NP_647733.1
• Gene: MEP-1 / 38327
• FlyBaseID: FBgn0035357
• Length: 1152
• Species: Drosophila melanogaster
• Sequence 2: NP_001256688.1
• Gene: pzf-1 / 188142
• WormBaseID: WBGene00011505
• Length: 504
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 103/553 - (18%)
• Similarity: 170/553 - (30%)
• Gaps: 208/553 - (37%)

  Fly   683 CEFCNFKSESAMAMANHYETPHMNGVLYKCNFCTFEIRNATEIVYHMEAVHNIKARLIKPLPYHQ 747
            |..|........::..|....||  ..:.|..|...|.....:..||:..|||....|
 Worm    14 CGICGKYFSDDESLREHRRQRHM--TCHMCLLCNRRIPENETLREHMKNKHNIWKLFI------- 69

  Fly   748 CPNCGFEDNGKAKLARHQPVCAKKFRPELNLAPPNDWEAPAKIPRIKPRHGLVGTATAYQAMAAQ 812
            |..|.:....:..|..|:.......||.|                :||           .||...
 Worm    70 CVCCNWSFGTEIYLKCHEECMKSTGRPGL----------------LKP-----------LAMPMT 107

  Fly   813 AAAQKAALANIQQQQAAAQARNNLQAAALAAQNAAKMRQRAPQPPKQNIVRNPAPVRGGNAMNAG 877
            |.|::|:..|...|..:....::                            :|:||.
 Worm   108 APAREASALNTDPQNGSDDVPHS----------------------------SPSPVP-------- 136

  Fly   878 LSLPNSYQLAAGQLVQASKKPMAGQPSISITPLPRQSSVGAGAGASSSKAPQAAAGMKPGQS-PS 941
                   .:|...::|||        |:.:.|:.     .|...::|:..|:......|.:. |.
 Worm   137 -------MIAENSIIQAS--------SLKMEPIE-----SADRSSASTSTPRTLVSGTPREKIPC 181

  Fly   942 G-------------NNKAQFVI----CEICDGYIKDLEQLRNHMQWMHKVKIHPKMIYNRPPLNC 989
            |             .::.:|.:    |.:|:..|.:.|.:|:||:..|.:    |.:|     ||
 Worm   182 GFCGKDFFHEGSLREHRRRFHMTGHTCLLCNRQIPENETVRDHMKSQHNI----KKVY-----NC 237

  Fly   990 QKCQFRFFTDQGLERHLLGSHGLV---------------------TSSMQE------AANKGKD- 1026
            ..|.:.|..    :.||: ||...                     |:|:::      ....|.|
 Worm   238 LCCNWTFLN----QVHLI-SHKTCLKQTGKPCCRPGHMEPLAIPRTASIRQFFTLKTETQSGDDD 297

  Fly  1027 --AG--------RCPVCGR-MYQWKLLNHVSRDHHMT--------------------LKPAH--- 1057
              ||        .|..||: .|..:.|:...|..||:                    ::..|
 Worm   298 SAAGSQLFSARLSCKSCGKFFYSERSLSKHHRQIHMSGHVCVLCNHQMPKTVTVQEHMEKEHNIR 362

  Fly  1058 LSYKCTVCTATFGMYKQFETHVYTAHS----------TVARKAMDS-----KKNSAQ-----SSG 1102
            |.:.|..|..:|...:...:||.....          .:.|.|.||     |::.||     |:.
 Worm   363 LVFNCRCCNWSFATRRCLMSHVECLKKAGDARNVKPVAIPRMAADSILQSLKESEAQEYPDFSAA 427

  Fly  1103 SGSGAGMSRSSLGAANDSLLKPLKI-NDEITII 1134
            |.:.:|.: |:|........|.||| .|.:.|:
 Worm   428 STTSSGPA-STLKTPRMDFKKNLKICTDAVQIL 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEP-1	NP_647733.1	C2H2 Zn finger	951..977	CDD:275371	8/25 (32%)
		C2H2 Zn finger	989..1010	CDD:275371	5/20 (25%)
pzf-1	NP_001256688.1	COG5236	<13..>62	CDD:227561	10/49 (20%)