DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MEP-1 and ztf-29

DIOPT Version :9

Sequence 1:	NP_001137875.1	Gene:	MEP-1 / 38327	FlyBaseID:	FBgn0035357	Length:	1152	Species:	Drosophila melanogaster
Sequence 2:	NP_499490.1	Gene:	ztf-29 / 176585	WormBaseID:	WBGene00013438	Length:	343	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	48/244 - (19%)
Similarity:	93/244 - (38%)	Gaps:	51/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PTTKLASASSSPKQSKPSADDVEQQVTTVEDDEEQVVEEQQEEDVHLPEAPSNEKLELLSAGGKD 79
            |::|....|.:|...       ..|:..:..:.....::||:..|..|..|::...:||:|
Worm   136 PSSKAMKTSDTPLTG-------HDQILALLSNLMSAQQQQQQAPVATPTIPASWIDQLLAA---- 189

  Fly    80 ISKEDVAQASPQAPVADEIMEVDGTEDVEENEVENDDEDSQITSSSSKEPKLDEEDEEATTNGDG 144
                 .....|..|.:........:.::|:.. |....|:.:||      .::..:|.|:|:|:.
Worm   190 -----TPALLPFMPSSSTFSASSSSSEMEQTP-EPSSLDTVLTS------MMNNNEEAASTSGEI 242

  Fly   145 DHEPEDEDDAQ-KIGSTAENSCEAEDPLGA--VTVPDDELASGKKAHLDGEESVASEGVVEEEPP 206
            ..|.|:|::.. .||...:....|   :||  ::|..::..|         .|::||..:...|.
Worm   243 KEEEEEEEEVDIDIGDEKDLLVRA---VGADFLSVKTEQPIS---------NSMSSESGIGSAPV 295

  Fly   207 AKQENGFGASPNQKENGQASIAEARAAIAPSDGGVVNLDEDSDEEMEDI 255
            :...:....||.:||...             |.|.|..::.|...::||
Worm   296 SNTPSPVATSPERKEENM-------------DVGRVKKEKKSKRSIDDI 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MEP-1	NP_001137875.1	BSP_II	<121..>226	CDD:283165	24/107 (22%)
		C2H2 Zn finger	951..977	CDD:275371
		C2H2 Zn finger	989..1010	CDD:275371
ztf-29	NP_499490.1	COG5236	<15..>92	CDD:227561
		C2H2 Zn finger	20..40	CDD:275368
		C2H2 Zn finger	47..68	CDD:275368
		C2H2 Zn finger	76..92	CDD:275368
		U2AF_lg	112..>191	CDD:273727	13/70 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100