DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pxn and Chl1

DIOPT Version :9

Sequence 1:NP_523891.2 Gene:Pxn / 38326 FlyBaseID:FBgn0011828 Length:1527 Species:Drosophila melanogaster
Sequence 2:XP_038964701.1 Gene:Chl1 / 89828 RGDID:620122 Length:1224 Species:Rattus norvegicus


Alignment Length:725 Identity:170/725 - (23%)
Similarity:265/725 - (36%) Gaps:198/725 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 VPKLPQD-TQTLDLRFNHIEELPANAFSGLAQLTTLFLN-------DNELAYL-QDGALNGLTAL 102
            |||.|:: .:.:|:.......||.|...|...|...::|       .:|..|: |.|.|      
  Rat   129 VPKFPKEKIEPIDVEEGDSIVLPCNPPKGHPPLHIYWMNIELEHIEQDERVYMSQKGDL------ 187

  Fly   103 RFVYLNN--NRLSRLPATIFQRMPRLEAIFLENNDIWQLPAGLFDNLPRLNRLIMYNNKLTQLPV 165
               |..|  .:.||.....|...|:|..|      :.::|.                 |||    
  Rat   188 ---YFANVEEKDSRNDYCCFAAFPKLRTI------VQKMPM-----------------KLT---- 222

  Fly   166 DGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRWHLDVQRQLVSISLTCAAPQMLQNQGFSSLGEHH 230
                 :|:||                      |.:.......||          ||..|      
  Rat   223 -----VNSLK----------------------HANDSSSSTEIS----------NQANS------ 244

  Fly   231 FKCAKPQFLVAPQDAQVAA--------GEQVELSCEVTGLPRPQITWMHNTQELGLEEQAQAEIL 287
            .|..||:.|:.|  ||:.:        |:.:.|.|...|||.|||.|    .:||.|       |
  Rat   245 IKQRKPKLLLPP--AQIGSASSKTVLKGDTLLLECFAEGLPTPQIEW----SKLGSE-------L 296

  Fly   288 PSG---------SLLIRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQV 343
            |.|         :|.|.:....|.|.|:|.|.|.:|. .|....::|.                 
  Rat   297 PKGRATIEIHEKTLKIENVSYQDRGNYRCTANNLLGK-ASHDFHVIVE----------------- 343

  Fly   344 WADAGTPMHGATPLPSPLPSPPHFTHQPHDQIVALHGSGHVLLDCAASGWPQPDIQWFVNGRQLL 408
                               .||.:..:|...:.:. ||..:|| |.|.|.|||.|:|.|||.. :
  Rat   344 -------------------EPPRWKKKPQSAVYST-GSNGILL-CEAEGEPQPTIKWRVNGLP-I 386

  Fly   409 QSTP---SLQLQANGSLILLQPNQLSAGTYRCEARNSLGSVQATARIELKELPEILTAPQSQTIK 470
            ::.|   .:......|...||||.  ...|:|||.|..|::.|.|.|::.::..::.....:..:
  Rat   387 ENHPFPGDVMFPREISFTNLQPNH--TAVYQCEASNIHGTILANANIDVVDVVPLIQTKNEENYE 449

  Fly   471 --LGKAFVLECDADGNPLPTIDWQL--NGVPLPGNTPDLQLENENTELVVGAARQEHAGVYRCTA 531
              :|.:..|.|:...:|..|:.|::  ...||.|..   ...:||..|.:....:|.||.|.|..
  Rat   450 TVVGYSAFLHCEYFASPKATVVWEVADETHPLEGGR---YHTHENGTLEIERTTEEDAGSYSCWV 511

  Fly   532 HNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQA---DQPEDGLQISWRHDGRL 593
            .|..|:..:.|.:.:   ::..:|.:.|.|........:||.|::   ...:..|::||..||..
  Rat   512 DNTMGKAVITANLDI---RNATKLRVFPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEA 573

  Fly   594 IDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTI-------RNNVDLA 651
            .:.|.....:..|.|| :|.:.|::..|.|.|.|..:......|....||:       ||.:...
  Rat   574 FEMNGTEDGRIVIDGA-NLTISNISGEDQGIYSCSAQTALDSTSGKTQVTVLGVPDPPRNLLLSE 637

  Fly   652 PGDRYVRIAFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYE 716
            ..:|.||::: ||..:.:..|:..:.....||.:  |..:.||.||    .||...:......|.
  Rat   638 RQNRSVRLSW-EAGDDHNSKISEYIVEFEGNREE--PGKWEELTRV----RGEETDVVLPLAPYV 695

  Fly   717 R-----TLVN 721
            |     |.||
  Rat   696 RYQFRVTAVN 705

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PxnNP_523891.2 LRR_RI 51..>161 CDD:238064 23/120 (19%)
leucine-rich repeat 54..77 CDD:275380 5/22 (23%)
LRR_8 55..112 CDD:290566 14/66 (21%)
leucine-rich repeat 78..101 CDD:275380 7/30 (23%)
leucine-rich repeat 102..125 CDD:275380 5/24 (21%)
LRR_8 124..184 CDD:290566 10/59 (17%)
leucine-rich repeat 126..149 CDD:275380 3/22 (14%)
LRR_4 148..185 CDD:289563 6/36 (17%)
leucine-rich repeat 150..173 CDD:275380 3/22 (14%)
Ig 240..325 CDD:299845 29/101 (29%)
IG_like 242..325 CDD:214653 29/99 (29%)
I-set 366..450 CDD:254352 29/86 (34%)
Ig 384..451 CDD:143165 26/69 (38%)
I-set 458..546 CDD:254352 20/91 (22%)
Ig 472..536 CDD:299845 18/65 (28%)
I-set 553..644 CDD:254352 23/93 (25%)
Ig 570..643 CDD:299845 19/75 (25%)
An_peroxidase 777..1317 CDD:281139
peroxidasin_like 898..1338 CDD:188658
VWC 1465..1523 CDD:278520
Chl1XP_038964701.1 Ig 34..125 CDD:416386
Ig strand A 34..38 CDD:409353
Ig strand A' 43..47 CDD:409353
Ig strand B 52..59 CDD:409353
Ig strand C 65..70 CDD:409353
Ig strand C' 73..75 CDD:409353
Ig strand D 81..84 CDD:409353
Ig strand E 89..93 CDD:409353
Ig strand F 104..112 CDD:409353
Ig strand G 115..125 CDD:409353
IgI_2_L1-CAM_like 134..224 CDD:409432 24/130 (18%)
Ig strand B 148..152 CDD:409432 1/3 (33%)
Ig strand C 162..166 CDD:409432 0/3 (0%)
Ig strand E 185..189 CDD:409432 2/12 (17%)
Ig strand F 200..205 CDD:409432 0/4 (0%)
Ig strand G 216..219 CDD:409432 0/2 (0%)
Ig 261..343 CDD:416386 26/93 (28%)
Ig strand B 273..277 CDD:409353 1/3 (33%)
Ig strand C 286..290 CDD:409353 3/7 (43%)
Ig strand E 308..312 CDD:409353 1/3 (33%)
Ig strand F 322..327 CDD:409353 2/4 (50%)
Ig strand G 335..338 CDD:409353 1/2 (50%)
Ig4_L1-NrCAM_like 347..434 CDD:409367 31/91 (34%)
Ig strand B 363..367 CDD:409367 2/4 (50%)
Ig strand C 376..380 CDD:409367 1/3 (33%)
Ig strand E 399..403 CDD:409367 0/3 (0%)
Ig strand F 413..418 CDD:409367 2/4 (50%)
Ig strand G 426..429 CDD:409367 1/2 (50%)
Ig 447..524 CDD:416386 20/79 (25%)
Ig strand A' 447..451 CDD:409353 0/3 (0%)
Ig strand B 454..463 CDD:409353 2/8 (25%)
Ig strand C 469..474 CDD:409353 2/4 (50%)
Ig strand C' 477..480 CDD:409353 0/2 (0%)
Ig strand D 485..490 CDD:409353 0/7 (0%)
Ig strand E 491..498 CDD:409353 2/6 (33%)
Ig strand F 505..513 CDD:409353 3/7 (43%)
Ig strand G 516..524 CDD:409353 2/7 (29%)
Ig 528..627 CDD:416386 24/99 (24%)
Ig strand A 528..534 CDD:409353 1/5 (20%)
Ig strand A' 537..542 CDD:409353 1/4 (25%)
Ig strand B 545..553 CDD:409353 3/7 (43%)
Ig strand C 564..568 CDD:409353 1/3 (33%)
Ig strand D 583..586 CDD:409353 0/2 (0%)
Ig strand E 589..593 CDD:409353 2/4 (50%)
Ig strand F 602..609 CDD:409353 3/6 (50%)
Ig strand G 616..620 CDD:409353 1/3 (33%)
FN3 627..716 CDD:238020 22/86 (26%)
fn3 730..811 CDD:394996
FN3 832..926 CDD:238020
FN3 931..1026 CDD:238020
Bravo_FIGEY 1120..1201 CDD:404722
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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