| Sequence 1: | NP_523891.2 | Gene: | Pxn / 38326 | FlyBaseID: | FBgn0011828 | Length: | 1527 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_024308853.1 | Gene: | TPO / 7173 | HGNCID: | 12015 | Length: | 947 | Species: | Homo sapiens |
| Alignment Length: | 732 | Identity: | 294/732 - (40%) |
|---|---|---|---|
| Similarity: | 434/732 - (59%) | Gaps: | 41/732 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 652 PGDRYVRIAFAEAAKEIDLAINNTLDMLFSNRSDKAPPNYGELLRVFRFPTGEARQLARAAEIYE 716
Fly 717 RTLVNIRKHVQEGDNLTMKSEEYEFRDLLSREHLHLVAELSGCMEHREMPNCTDMCFHSRYRSID 781
Fly 782 GTCNNLQHPTWGASLTAFRRLAPPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSL--VATKEI 844
Fly 845 TPDARITHMVMQWGQFLDHDLDHAIPSVSSESW-DGIDCKKSCEMAPPCYPIEVPPNDPRVRNRR 908
Fly 909 CIDVVRSSAICGSGMTSLFF---DSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLL 970
Fly 971 RVGVHFPRQKD----MLPF--------AAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMH 1023
Fly 1024 TIWMREHNRIASKLKQINSHWDGDTLYQEARKIVGAQMQHITFKQWLPLIIG-ESGMEMMGEYQG 1087
Fly 1088 YNPQLNPSIANEFATAALRFGHTIINPILHRLNETFQPIPQ-GHLLLHKAFFAPWRLAYEGGVDP 1151
Fly 1152 LMRGFLAVPAKLKTPDQNLNTELTEKLFQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTV 1216
Fly 1217 AQDFEDLAGEISSAEIRQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDG 1281
Fly 1282 DRLYYENPGVFSPEQLTQIKQANFGRVLCDVGDNFDQVTENVFILAKHQGGYKKCEDIIGINLYL 1346
Fly 1347 WQEC----GRCNSPPAI 1359 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pxn | NP_523891.2 | LRR_RI | 51..>161 | CDD:238064 | |
| leucine-rich repeat | 54..77 | CDD:275380 | |||
| LRR_8 | 55..112 | CDD:290566 | |||
| leucine-rich repeat | 78..101 | CDD:275380 | |||
| leucine-rich repeat | 102..125 | CDD:275380 | |||
| LRR_8 | 124..184 | CDD:290566 | |||
| leucine-rich repeat | 126..149 | CDD:275380 | |||
| LRR_4 | 148..185 | CDD:289563 | |||
| leucine-rich repeat | 150..173 | CDD:275380 | |||
| Ig | 240..325 | CDD:299845 | |||
| IG_like | 242..325 | CDD:214653 | |||
| I-set | 366..450 | CDD:254352 | |||
| Ig | 384..451 | CDD:143165 | |||
| I-set | 458..546 | CDD:254352 | |||
| Ig | 472..536 | CDD:299845 | |||
| I-set | 553..644 | CDD:254352 | |||
| Ig | 570..643 | CDD:299845 | |||
| An_peroxidase | 777..1317 | CDD:281139 | 250/559 (45%) | ||
| peroxidasin_like | 898..1338 | CDD:188658 | 199/456 (44%) | ||
| VWC | 1465..1523 | CDD:278520 | |||
| TPO | XP_024308853.1 | thyroid_peroxidase | 179..746 | CDD:188657 | 249/575 (43%) |
| CCP | 754..807 | CDD:153056 | 2/7 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2408 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D276568at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11475 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2739 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 5 | 4.950 | |||||