DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pxn and APL1A

DIOPT Version :9

Sequence 1:NP_523891.2 Gene:Pxn / 38326 FlyBaseID:FBgn0011828 Length:1527 Species:Drosophila melanogaster
Sequence 2:XP_001688066.1 Gene:APL1A / 5666905 VectorBaseID:AGAP007036 Length:428 Species:Anopheles gambiae


Alignment Length:203 Identity:51/203 - (25%)
Similarity:92/203 - (45%) Gaps:29/203 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 CLERTVR--CIRAKLSAVPKLPQDTQTLDLRF-----------------NHIEELPANAFSGLAQ 77
            |:|:.::  |:...:..      |.|:.|:.|                 :.:.:|||.:.:...|
Mosquito    55 CIEKNLQYDCVFYNVHI------DMQSQDVYFGFDDITLNNQKNVTFKNSTMRKLPAASLASFRQ 113

  Fly    78 LTTLFLNDNELAYLQDGALNGLTALRFVYLNNNRLSRLPATIFQRMPRLEAIFLENNDIWQLPAG 142
            :..|.||..::..:...|......::.:|:..|.:..||..:||.:|.|..:.||.||:..||.|
Mosquito   114 VEVLNLNGLQIEEIDTNAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPSLTVLVLERNDLTSLPRG 178

  Fly   143 LFDNLPRLNRLIMYNNKLTQLPVDGFNRLNNLKRLRLDGNAIDCNCGVYSLWRRWHLDVQRQLVS 207
            :|.|.|:|..|.|.||.|.::..:.|.....|:.|:|..|.: .:..:..:...:|::|...|:|
Mosquito   179 IFHNTPKLTMLSMSNNNLERIEDETFQATTTLQNLQLSSNRL-THVDLALIPSLFHVNVSYNLLS 242

  Fly   208 ISLTCAAP 215
               |.|.|
Mosquito   243 ---TLAIP 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PxnNP_523891.2 LRR_RI 51..>161 CDD:238064 35/126 (28%)
leucine-rich repeat 54..77 CDD:275380 6/39 (15%)
LRR_8 55..112 CDD:290566 13/73 (18%)
leucine-rich repeat 78..101 CDD:275380 4/22 (18%)
leucine-rich repeat 102..125 CDD:275380 6/22 (27%)
LRR_8 124..184 CDD:290566 23/59 (39%)
leucine-rich repeat 126..149 CDD:275380 10/22 (45%)
LRR_4 148..185 CDD:289563 12/36 (33%)
leucine-rich repeat 150..173 CDD:275380 7/22 (32%)
Ig 240..325 CDD:299845
IG_like 242..325 CDD:214653
I-set 366..450 CDD:254352
Ig 384..451 CDD:143165
I-set 458..546 CDD:254352
Ig 472..536 CDD:299845
I-set 553..644 CDD:254352
Ig 570..643 CDD:299845
An_peroxidase 777..1317 CDD:281139
peroxidasin_like 898..1338 CDD:188658
VWC 1465..1523 CDD:278520
APL1AXP_001688066.1 LRR_8 112..172 CDD:290566 16/59 (27%)
leucine-rich repeat 114..137 CDD:275380 4/22 (18%)
leucine-rich repeat 138..161 CDD:275380 6/22 (27%)
LRR_RI 160..402 CDD:238064 30/92 (33%)
LRR_8 160..220 CDD:290566 23/59 (39%)
leucine-rich repeat 162..185 CDD:275380 10/22 (45%)
leucine-rich repeat 186..209 CDD:275380 7/22 (32%)
leucine-rich repeat 210..230 CDD:275380 4/20 (20%)
leucine-rich repeat 231..255 CDD:275380 7/20 (35%)
LRR_8 270..327 CDD:290566
leucine-rich repeat 271..292 CDD:275380
leucine-rich repeat 293..316 CDD:275380
LRR_8 316..373 CDD:290566
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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