Protein Alignment Pxn and LOC1270890

DIOPT Version :10

• Sequence 1: NP_523891.2
• Gene: Pxn / 38326
• FlyBaseID: FBgn0011828
• Length: 1527
• Species: Drosophila melanogaster
• Sequence 2: XP_309590.6
• Gene: LOC1270890 / 1270890
• VectorBaseID: AGAMI1_007319
• Length: 797
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 220/711 - (30%)
• Similarity: 334/711 - (46%)
• Gaps: 113/711 - (15%)

  Fly   701 PTGEARQLARAAE----------------IYERTLVNIRKHVQEGDNLTMKSE--EYEFRDLLSR 747
            |..|..||.|.||                ..|.|.......:...|:: :.||  :...:|:|:.
Mosquito   138 PYQEQEQLLRRAEKMAYHELETFLTHDGSAEEDTPATFHGELPLSDDV-LSSELVQQGLQDVLTW 201

  Fly   748 EHLHLVAELSGCMEHREMPNCTDMCF--------HSRYRSIDGTCNNLQ--HPTWGASLTAFRRL 802
            :.|:.::. ...:|:.:.|.   .|.        |||||..||.|||::  ...|||:.....||
Mosquito   202 QALNSISN-GSAIEYFQRPK---RCLVGPACDKGHSRYRRFDGRCNNIEPGGSLWGAAGYPMERL 262

  Fly   803 APPIYENGFSMPVGWTKGMLYSGHAKPSARLVSTSLVATKEITPDARITHMVMQWGQFLDHDLDH 867
            .||.|.:|...|    :.:.::|...||||.:|::|.|... .|.|....:.||:||||.||...
Mosquito   263 LPPAYGDGIWAP----RIVSHTGRYLPSARKLSSTLFADLH-HPHATCNVLFMQFGQFLAHDFSR 322

  Fly   868 AIPSVSSESWDGIDCKKSC----------EMAPPCYPIEVPPNDPRVRNR--RCIDVVRSSAI-- 918
            ..|         |..|..|          :..|.|.||.|...|......  ||:..:||:..
Mosquito   323 NKP---------IKTKAKCCTEDGTGRVKDAFPGCMPIPVSSGDYFYSQHGVRCLHFMRSAVAPT 378

  Fly   919 --CGSGMTSLFFDSVQHREQINQLTSYIDASQVYGYSTAFAQELRNLTSQEGLLRVGVHFPRQKD 981
              |         .||.|..|::.::.:||.|.:||..:..:..||.|  :.|.|:...|.....:
Mosquito   379 RDC---------HSVGHGRQLSAVSHFIDGSAIYGTDSKQSHALRAL--EGGRLKSLFHRRFHNE 432

  Fly   982 MLPFAAPQDGMDCRRNLDENTMSCFVSGDIRVNEQVGLLAMHTIWMREHNRIASKLKQINSHWDG 1046
            :.|....:|..|....:      ||::||.|.|:.:.|:|:||:::|||||:|.:|:::|.||..
Mosquito   433 LPPLDHTKDACDPAAEM------CFLTGDGRSNQLISLVAVHTLFLREHNRLARQLQKLNPHWSD 491

  Fly  1047 DTLYQEARKIVGAQMQHITFKQWLPLIIGESGMEMM-------GEY-QGYNPQLNPSIANEFATA 1103
            .||:||||:||.||:|||.:.::||.::|...|.:.       |.| :.|:|..|||:::||..|
Mosquito   492 RTLFQEARRIVIAQLQHIAYGEYLPRVVGPRYMSLYRLHLPVPGTYSEFYSPHTNPSVSSEFTVA 556

  Fly  1104 ALRFGHTIINPILHRLNETFQPIPQGHLLLHKAFFAPWRLAYEGGVDPLMRGFLAVPAKLKTPDQ 1168
            |.||||:.:...|        .:..|.:.....|..|.|.......|.|:......|  :::.|:
Mosquito   557 AFRFGHSTVPSKL--------DLQDGPVDTWLTFLNPTRFRERTFYDDLLWSLQRQP--MQSVDE 611

  Fly  1169 NLNTELTEKL-FQTAHAVALDLAAINIQRGRDHGMPGYNVYRKLCNLTVAQDFEDLAGEISSAEI 1232
            ..:|.||..| .:......:|||||||||||||.:..||.||:|.....|..|:|...|:.|
Mosquito   612 LFSTSLTRFLNVKPGKQHGVDLAAINIQRGRDHAVRPYNDYRRLSGRAGAYSFDDFGPEVGS--- 673

  Fly  1233 RQKMKELYGHPDNVDVWLGGILEDQVEGGKVGPLFQCLLVEQFRRLRDGDRLYYE-----NPGVF 1292
              |::.||.|||:||:::|||||..|:||.||..|..|:..||.:.:.|||.:|.     |||.|
Mosquito   674 --KLRALYPHPDDVDLYVGGILEPPVDGGVVGETFAELIANQFAKFQRGDRYFYSNGPDTNPGHF 736

  Fly  1293 SPEQLTQIKQANFGRVLC-DVGDNFD-QVTENVFILAKHQGGYKKC--EDIIGINLYLWQE 1349
            :..||.:|::.....::| :.||... .|..:.|.|.........|  .:|..::|..|::
Mosquito   737 TVPQLKEIQRVTLASLICANAGDPHQMHVVPDAFALPHEDNRPIDCTAPEIPRLDLSWWRD 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxn	NP_523891.2	leucine-rich repeat	54..77	CDD:275380
		LRR	<55..>184	CDD:443914
		leucine-rich repeat	78..101	CDD:275380
		leucine-rich repeat	102..125	CDD:275380
		leucine-rich repeat	126..149	CDD:275380
		leucine-rich repeat	150..173	CDD:275380
		Ig_3	235..311	CDD:464046
		Ig	366..450	CDD:472250
		Ig strand B	384..388	CDD:409544
		Ig strand C	397..401	CDD:409544
		Ig strand E	420..424	CDD:409544
		Ig strand F	434..439	CDD:409544
		Ig strand G	447..450	CDD:409544
		Ig_3	458..533	CDD:464046
		Ig	553..644	CDD:472250
		Ig strand B	570..574	CDD:409353
		Ig strand C	584..588	CDD:409353
		Ig strand E	610..614	CDD:409353
		Ig strand F	624..629	CDD:409353
		Ig strand G	638..641	CDD:409353
		peroxidasin_like	898..1338	CDD:188658	152/463 (33%)
		VWC	1465..1523	CDD:278520
LOC1270890	XP_309590.6	None