DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16985 and ACOT13

DIOPT Version :9

Sequence 1:	NP_647730.1	Gene:	CG16985 / 38323	FlyBaseID:	FBgn0035355	Length:	149	Species:	Drosophila melanogaster
Sequence 2:	NP_060943.1	Gene:	ACOT13 / 55856	HGNCID:	20999	Length:	140	Species:	Homo sapiens

Alignment Length:	134	Identity:	53/134 - (39%)
Similarity:	83/134 - (61%)	Gaps:	7/134 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DFVKQMSEYASGSNGFDRVLKMIKITGGGDGRAIGEFTVANEHLNRQGTLHGGLTATIVDNCTTY 73
            :.:|.|::    :..|:|||..|.:.....|:.|.|..|..||.|..||||||||||:|||.:|.
Human    10 EVIKAMTK----ARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTM 70

  Fly    74 ALM--SKGSHPGVTANLNVSYIAAAKPGELIEIDCNTVRAGKKMAYLDCILRRKSDGKIIAKGGQ 136
            ||:  .:|: |||:.::|::|::.||.||.|.|..:.::.||.:|:....|..|:.||:||:|..
Human    71 ALLCTERGA-PGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRH 134

  Fly   137 VKYI 140
            .|::
Human   135 TKHL 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16985	NP_647730.1	PaaI_thioesterase	31..140	CDD:239527	47/110 (43%)
ACOT13	NP_060943.1	PaaI_thioesterase	25..138	CDD:239527	48/113 (42%)
		Coenzyme A binding. /evidence=ECO:0000269\|PubMed:19170545, ECO:0007744\|PDB:3F5O	90..95		1/4 (25%)
		Coenzyme A binding. /evidence=ECO:0000269\|PubMed:19170545, ECO:0007744\|PDB:3F5O	108..113		2/4 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158061
Domainoid	1	1.000	64	1.000	Domainoid score	I10130
eggNOG	1	0.900	-	-		E1_COG2050
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I5025
Isobase	1	0.950	-	0	Normalized mean entropy	S4138
OMA	1	1.010	-	-		QHG55852
OrthoDB	1	1.010	-	-		D1607235at2759
OrthoFinder	1	1.000	-	-		FOG0002696
OrthoInspector	1	1.000	-	-		otm40609
orthoMCL	1	0.900	-	-		OOG6_101688
Panther	1	1.100	-	-	LDO	PTHR21660
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2936
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.720