Protein Alignment CG16984 and ENKUR

DIOPT Version :10

• Sequence 1: NP_647729.1
• Gene: CG16984 / 38322
• FlyBaseID: FBgn0062517
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_659447.1
• Gene: ENKUR / 219670
• HGNCID: 28388
• Length: 256
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 74/238 - (31%)
• Similarity: 117/238 - (49%)
• Gaps: 35/238 - (14%)

  Fly    76 KSAHRTMGCAHTPIDPPCAYLRKSQGIKW---RRENTHKCPKMPPMP-----PLPPPGSGGKKPA 132
            |:|.:|||.|...:..|..:|:|....|.   ::......||.|.:|     |:....||
Human    43 KTAMKTMGPAKVEVPSPKDFLKKHSKEKTLPPKKNFDRNVPKKPAVPLKTDHPVMGIQSG----- 102

  Fly   133 MVPNFIKRNKICAGQTVPCPPPPRYVDTPVGARHDLLNSGLVPQFICRKDFGKVPVYLKKTKRML 197
              .|||..|.......|...|.|.|||...|.:|||..|||||::|.:||:|..|.|
Human   103 --KNFINTNAADIIMGVAKKPKPIYVDKRTGDKHDLEPSGLVPKYINKKDYGVTPEY-------- 157

  Fly   198 ADMNAVCAKEQARLLELCRGIKGFTRASVQSSGPPPMPGMRVMEQAERNEILEGLRLSLTEMTKQ 262
                 :|.:.:    |:.:..:.:.|...::.   ....|:.:...||..:|:||:.:..|:.|:
Human   158 -----ICKRNE----EIKKAQEDYDRYIQENL---KKAAMKRLSDEEREAVLQGLKKNWEEVHKE 210

  Fly   263 YQSMSLLIDSIAKRQRKSKLESDLRQVEQDILLIETTPIIYVS 305
            :||:|:.||||.|:.||.:||.:::|:|.||.:||...|||::
Human   211 FQSLSVFIDSIPKKIRKQRLEEEMKQLEHDIGIIEKHKIIYIA 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16984	NP_647729.1	Enkurin	184..298	CDD:464004	31/113 (27%)
ENKUR	NP_659447.1	SH3-binding. /evidence=ECO:0000255	83..89		3/5 (60%)
		Enkurin	152..246	CDD:464004	31/113 (27%)
		Interaction with TRPC proteins. /evidence=ECO:0000250|UniProtKB:Q6SP97	160..255		31/101 (31%)