Protein Alignment dos and LOC1274303

DIOPT Version :10

• Sequence 1: NP_523890.2
• Gene: dos / 38321
• FlyBaseID: FBgn0016794
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_313403.4
• Gene: LOC1274303 / 1274303
• VectorBaseID: AGAMI1_011651
• Length: 1748
• Species: Anopheles gambiae
• Alignment Length: 1057
• Identity: 205/1057 - (19%)
• Similarity: 327/1057 - (30%)
• Gaps: 388/1057 - (36%)

  Fly   131 DENRTQHTSSSGGLSNSTQNTTTTSLHSSAG-TTAP------------QASVPNAGGSAQLRRPA 182
            |.:....:|..||..:.|.|.|.|:.||..| ..||            |:|:|...     |.|.
Mosquito   192 DSSGVSSSSRGGGGHSGTANGTATNGHSQMGPPVAPTRKKRLAPRPPSQSSIPEVS-----RVPP 251

  Fly   183 VIEEQPMPSNAG-----NNNSDSVYVNTE---YSNRETMLCDANFDQQELLSA----AQQQPPPS 235
              :..|..||.|     :...|.::...:   ||.:...:...|...:||..|    ........
Mosquito   252 --QTPPQQSNGGTPGDKHGTDDHIFKEPQLPPYSRQNFHVSTPNLYDRELKPADIINNNGNGSVH 314

  Fly   236 PATA----------LYLNHSALIQAQAAAAAAEQLQQQQQQAARLAVSANGVVRKLPEHLVL--- 287
            |.||          ::.|::.:..||:|     .|.::.::......::...::..|..:.:
Mosquito   315 PKTANGDRNGYSADVHNNNNNIHDAQSA-----MLGEEDRKNLINTKTSYSTLKNRPTSMYIIRE 374

  Fly   288 --TQQTLAEAAAQ-------QHSSVQASPALSTASGPY--------IPISECFSGSPRFLPGVPL 335
              |..||..::..       .|...:||.:.|.|..|.        .|.....|.:.:.....|.
Mosquito   375 PDTTNTLQRSSENGGSMVDIHHHHSRASSSCSDAKDPRDFQDMPEPTPRKRLNSSAKKSKAPAPP 439

  Fly   336 PGADLAIPNNPTTP-------------------LNNLDPKFYDTP-RSHNN--IGLNLTNDQ--- 375
            |.|.........||                   ::..|..|...| .:|.|  ..||..|..
Mosquito   440 PRAKTTTITPVPTPSPRALTRSTLDLLRDNDAAISETDSNFSSEPDDTHRNRESRLNAVNGSVHH 504

  Fly   376 -SYSPKITNLSLQQL----------------ANNNASK-QRSDSDSESVFTD------DDEWAHP 416
             .|:|:..|:|...|                .||:..| |::.|.|.||...      .|..:.|
Mosquito   505 APYTPQQQNVSKVMLNVEQAPLNDPVVTSTTPNNSEKKHQKNGSTSSSVSIKIVSNGVGDAQSKP 569

  Fly   417 ---LPLRENV----------DRSTRPSDSSIENE----------SFVLTYSQRFSKMPEE----- 453
               .|:...|          |..|.|.|:|.:.|          :.:...:|..::|.:|
Mosquito   570 SSTTPIVSKVQIGGNLPAPLDLPTSPGDNSSDEEIKIYNIESGKALIKKKTQNGTEMEQEQKKAT 634

  Fly   454 --GGAIVPPAEKSSKLAGAASLP------EAGDQ----GTLD------KLAKVLKNKNNLI---- 496
              ||..:....|.|...|.:..|      ::.:|    .|.|      ||....|..::.|
Mosquito   635 PGGGTTLTNGAKVSSSNGTSIEPNGDTNQQSAEQQTNGATADEEQWTYKLPAPPKFADSSIKTSD 699

  Fly   497 -----------LDFKENEKIPRD-LPQLSD--TENTSPAIVARRNAHSAFIEESYDIPRSH---Q 544
                       ..|.:|..:..| |..:||  ||...|.|..|       ::...|:....   |
Mosquito   700 YDERGQFYRPASTFVDNTTLRSDMLTVVSDEQTERIEPFIQER-------LQTMLDLTAGRDTMQ 757

  Fly   545 QPYYNVNQLLGERPVTSPHNSNPIAAST------------PNLMAADL------GAVAAISAAAN 591
            .|:|..  :|..||      .:|::.||            |..:::||      ||.:...|...
Mosquito   758 PPFYPT--VLDHRP------DSPVSVSTETDATMHVSEDVPPHISSDLEDGYRVGAESRSEANGA 814

  Fly   592 PGLMGEAQAV--------------------------------ASSPTSARTLPRHCYTNAAPTKM 624
            |....||:.|                                ..:||.:||...:...::..:::
Mosquito   815 PDSSQEAREVWLQTLEKRREKIIEGELSTLSESIGSGGKGPEVDAPTVSRTQSVNDRKSSVMSEL 879

  Fly   625 -----EGNVFRYDFMEQADCPPVNRK----------------------------LKPKV-----A 651
                 ||  ......|:.:...|||.                            ::.:|     |
Mosquito   880 NQLLREG--VELSRKEETEIAVVNRSSLANFKISTYSSSENKENIITSTTTTTIVEKQVQQQNHA 942

  Fly   652 GG--LPVV--------------EDKPPEEFP-----AKPPVGVDQLTNKLGAAQLQ-----QPIG 690
            ||  :|||              |::..||..     .:..:.||.:|.:...:..|     .|:|
Mosquito   943 GGNDVPVVPNGASDAKHVPECQEEEEEEEVQEVDVIIRRKISVDSITVRKPHSLTQSSDEDDPVG 1007

  Fly   691 PPSVDRKCKPNAY-KLGNSA--TMSPATRRSSGAPLSMVLPHETDVHSPAAANA--FFHETRTLP 750
            .       :.|.| ..|.||  .::|..|||    |:|:      ..||...|.  .||.||:
Mosquito  1008 R-------QTNGYGAAGASAKKELAPVKRRS----LTML------NKSPRVINRSDSFHSTRS-- 1053

  Fly   751 RQQHRHHPNSPGSMS-------------------VQHQRTASAAAAMMSLTAAAAPKQQAAAQTE 796
              .:....|||....                   :..||..:.||...||..||....:..:.:|
Mosquito  1054 --DYIQSLNSPAQTGTSTSGPLHLTPRSTSYISLIGAQRWENRAATSASLVTAANSFNRRKSASE 1116

  Fly   797 HKLQYFDLDVTNKPPL---------LNRS-SMSVGNLYSQGGNGASGMRFAGVEAGGARAPVPSS 851
                   |.:.:.|.|         ||.| ..|:.||:...|:...|            :|....
Mosquito  1117 -------LSICDSPSLQSLEVIKNILNTSRKNSINNLHQTNGSAVEG------------SPADEG 1162

  Fly   852 VVYRSVDFVKTEAFKRI 868
            :|..|:..:|..:|..|
Mosquito  1163 IVLPSMAAIKRNSFTDI 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dos	NP_523890.2	PH_Gab2_2	2..115	CDD:241535
LOC1274303	XP_313403.4	None