Protein Alignment KIF11 and Kif11

DIOPT Version :10

• Sequence 1: NP_004514.2
• Gene: KIF11 / 3832
• HGNCID: 6388
• Length: 1056
• Species: Homo sapiens
• Sequence 2: NP_001162583.1
• Gene: Kif11 / 171304
• RGDID: 621258
• Length: 1056
• Species: Rattus norvegicus
• Alignment Length: 1056
• Identity: 848/1056 - (80%)
• Similarity: 952/1056 - (90%)
• Gaps: 1/1056 - (0%)

Human     1 MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKT 65
            |||||:||:||||||||||||||||||||||||||:|||:||||..||||||||.||.||:||||
  Rat     1 MASQPSSSSKKKEEKGKNIQVVVRCRPFNLAERKANAHSVVECDHARKEVSVRTAGLTDKTSRKT 65

Human    66 YTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||
  Rat    66 YTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEVYTWEED 130

Human   131 PLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVI 195
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
  Rat   131 PLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLSPSSDVSERLQMFDDPRNKRGVI 195

Human   196 IKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGK 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 IKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGK 260

Human   261 LNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLG 325
            ||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||
  Rat   261 LNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHIPYRESKLTRILQDSLG 325

Human   326 GRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLA 390
            ||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||
  Rat   326 GRTRTSIIATISPASLNLEETLSTLEYAHRAKNIMNKPEVNQKLTKKALIKEYTEEIERLKRDLA 390

Human   391 AAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQ 455
            |||||||||||||:||.|:||:|||||||.||.||||.:||||::..|||.|::.||:|||||||
  Rat   391 AAREKNGVYISEESFRAMNGKVTVQEEQIAELAEKIGVLEEELSKAAELFTDSEKELNQCKSDLQ 455

Human   456 NKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRK 520
            .||||||||||||||||||||||||::||||.||:|||:.||||||||:|||:||||||||||||
  Rat   456 TKTQELETTQKHLQETKLQLVKEEYVSSALERTEKKLHETASKLLNTVKETTRDVSGLHSKLDRK 520

Human   521 KAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVA 585
            :|:|.||||||:.||::|:||||||||||:|||.||||||:|||.|||||:||||||||||:|.|
  Rat   521 RAIDAHNAEAQESFGRSLSSLFNNMEELIRDGSEKQKAMLDVHKALFGNLMSSSVSALDTISTTA 585

Human   586 LGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI 650
            |.||.||||||...||||.:|||:||||||:||||||..|:.|.|:|.:||:.|::|.|||||.|
  Rat   586 LESLMSIPENVLARVSQISDMILEEQSLAAQSKTVLQGSIDELVTNLFTSLKTIIAPGVVSILNI 650

Human   651 NSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIK 715
            |.||:|||:.|:|:|:|:||||:|:|.||||||||||||:|||:.|||||||.||||||||||||
  Rat   651 NRQLQHIFRASVTMAEKVEDQKREIDSFLSILCNNLHELRENTVSSLVESQKLCGNLTEDLKTIK 715

Human   716 QTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780
            :|||||||:|.:.|.|||||||:|..||||||:|:|||.::||.||:||.|.||:|..|||||..
  Rat   716 ETHSQELCQLSSSWAERFCALEKKYANIQKPLNSIQENTERKSTDIINKTTVHSKKILADSDGLL 780

Human   781 QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELH 845
            ||||:||:|||:|||:||.|...|:.|||.:|||..|||.:|||.||:||:||.|.|::|::||.
  Rat   781 QELRHFNEEGTQLVEDSVGHCGSLSSNLETVSQEITQRCGTLNTSTVHFSDQWASCLSKRKEELQ 845

Human   846 NLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLN 910
            ||:|.|:.|||||||:||||..|.:||.|.||:.|:.|:|.||:|..|.:|||::|||.||||||
  Rat   846 NLMEFVNGCCEASSSEITEKIRGHRAAIESQHSSFVVQITSDEEKFKAGSLELDKTIKTGLTKLN 910

Human   911 CFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNCSENNKEETIPD 975
            |||:||||||||||.||:||:||||||||||||||.|||||::|||:.||||||||::| ||..|
  Rat   911 CFLQQDLKLDIPTGMTPERKNYLYPSTLVRTEPREQLLDQLQKKQPKPLMMLNCSESSK-ETSQD 974

Human   976 VDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERSKVEETTE 1040
            ::.:..||.|.|||.:||||.|....||||.||||||||||.|||||||||:|.:|:.||||.:|
  Rat   975 MEEDREVLEQSTEELVSQEPCVHTSADCSSSGGVPFFQHKKPHGKDKENRGLNPVEKGKVEEASE 1039

Human  1041 HLVTKSRLPLRAQINL 1056
            |.::||||||||.|||
  Rat  1040 HSISKSRLPLRASINL 1055

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIF11	NP_004514.2	KISc_BimC_Eg5	16..368	CDD:276815	340/351 (97%)
		PRK12704	350..>508	CDD:237177	131/157 (83%)
		YhaN	380..>761	CDD:443752	286/380 (75%)
		Microtub_bind	916..1053	CDD:464048	96/136 (71%)
Kif11	NP_001162583.1	KISc_BimC_Eg5	16..368	CDD:276815	340/351 (97%)
		PRK12704	350..>508	CDD:237177	131/157 (83%)
		YhaN	380..>785	CDD:443752	302/404 (75%)
		Microtub_bind	916..1052	CDD:464048	96/136 (71%)