DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16758 and pnp4a

DIOPT Version :9

Sequence 1:	NP_001261330.1	Gene:	CG16758 / 38315	FlyBaseID:	FBgn0035348	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001002102.1	Gene:	pnp4a / 415192	ZFINID:	ZDB-GENE-040625-83	Length:	291	Species:	Danio rerio

Alignment Length:	286	Identity:	138/286 - (48%)
Similarity:	187/286 - (65%)	Gaps:	2/286 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 NEDTYPYEVIEEIADFITKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHA 172
            ::|...:|..:..||::...:..|||:.||||||||.|||.::....|:|..||.||.|||:|||
Zfish     3 SKDQICHEDYQRAADWLLSQTQHRPKVAIICGSGLGMLADGLKCQDSFKYSDIPGFPQSTVKGHA 67

  Fly   173 GRLVVGTLEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIM 237
            ||||.|.|:|.|.:.||||||.|||:.|:|.:.||||.||.||:.|..|||||.:...:..||||
Zfish    68 GRLVFGELKGKTCVCMQGRFHMYEGHSLSKVTFPVRVFKLLGVDTLIVTNAAGSLADSYNCGDIM 132

  Fly   238 LMHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVYSCL 302
            ::.||:|..|.||.:||.||||.:||||||.:...|::.|...|::|.|.||:...:..|||..:
Zfish   133 IIRDHINFPGLAGLNPLNGPNDEKFGPRFPPMSGVYDRGLRKMALDICKGMGVSQYVQEGVYCMV 197

  Fly   303 GGPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDKKDDEANHD 367
            ||||:|:|||.:.|..:|||||||||..||:.|.||.::||..||||||....|.|  ::..||:
Zfish   198 GGPNFESIAEARLLHRLGVDAVGMSTAPEVLVASHCGIRVFGLSLITNKVVKSYED--NETVNHE 260

  Fly   368 EVMAVAKNRQKACCELVSRLIREIHL 393
            .|:.|:|.|.:....||:.||..:.:
Zfish   261 AVLEVSKMRSETLQALVTELISRMDI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16758	NP_001261330.1	PRK08202	113..391	CDD:236183	137/277 (49%)
CG16758	NP_001261330.1	XapA	116..391	CDD:223084	136/274 (50%)
pnp4a	NP_001002102.1	PRK08202	9..284	CDD:236183	137/276 (50%)
pnp4a	NP_001002102.1	XapA	13..284	CDD:223084	136/272 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580629
Domainoid	1	1.000	295	1.000	Domainoid score	I1457
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	308	1.000	Inparanoid score	I2603
OMA	1	1.010	-	-		QHG58962
OrthoDB	1	1.010	-	-		D1078969at2759
OrthoFinder	1	1.000	-	-		FOG0001804
OrthoInspector	1	1.000	-	-		otm24373
orthoMCL	1	0.900	-	-		OOG6_101826
Panther	1	1.100	-	-	O	PTHR11904
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2236
SonicParanoid	1	1.000	-	-		X1164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800