DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16758 and Pnp

DIOPT Version :9

Sequence 1:	NP_001261330.1	Gene:	CG16758 / 38315	FlyBaseID:	FBgn0035348	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_006251919.1	Gene:	Pnp / 290029	RGDID:	1597189	Length:	289	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	142/283 - (50%)
Similarity:	192/283 - (67%)	Gaps:	2/283 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 EDTYPYEVIEEIADFITKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAG 173
            |:.:.||..:..|:::...:..||::.:|||||||.|...:..|:.|:|.:|||||.|||:||||
  Rat     2 ENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAG 66

  Fly   174 RLVVGTLEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIML 238
            |||.|.|.|.:.:.||||||.||||.|:|.:.||||..|.||:.|..||||||:||:|.||||||
  Rat    67 RLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIML 131

  Fly   239 MHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVYSCLG 303
            :.||:|:.||.|.:||:||||.|||.||||:.::|::|:..||....|.||.:..:..|.|....
  Rat   132 IRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSA 196

  Fly   304 GPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDKKDDEANHDE 368
            ||.:||:||...|||:|.||||||||.|||.||||.::||.|||||||...:|::.  ::|:|.|
  Rat   197 GPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNL--EKASHQE 259

  Fly   369 VMAVAKNRQKACCELVSRLIREI 391
            |:...|...:...:.||.|:..|
  Rat   260 VLEAGKAAAQKLEQFVSILMESI 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16758	NP_001261330.1	PRK08202	113..391	CDD:236183	140/277 (51%)
CG16758	NP_001261330.1	XapA	116..391	CDD:223084	138/274 (50%)
Pnp	XP_006251919.1	XapA	11..276	CDD:223084	135/266 (51%)
Pnp	XP_006251919.1	PNPH	26..280	CDD:273764	135/255 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340800
Domainoid	1	1.000	277	1.000	Domainoid score	I1664
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H227
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2693
OMA	1	1.010	-	-		QHG58962
OrthoDB	1	1.010	-	-		D1078969at2759
OrthoFinder	1	1.000	-	-		FOG0001804
OrthoInspector	1	1.000	-	-		oto97043
orthoMCL	1	0.900	-	-		OOG6_101826
Panther	1	1.100	-	-	O	PTHR11904
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1164
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810