DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16758 and SPAC1805.16c

DIOPT Version :9

Sequence 1:	NP_001261330.1	Gene:	CG16758 / 38315	FlyBaseID:	FBgn0035348	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_593927.1	Gene:	SPAC1805.16c / 2542435	PomBaseID:	SPAC1805.16c	Length:	315	Species:	Schizosaccharomyces pombe

Alignment Length:	307	Identity:	131/307 - (42%)
Similarity:	178/307 - (57%)	Gaps:	28/307 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 TPQSLLGNGKIQCELTHEELRALRVLNEDTYPYEVIEEIADFITKGSGMRPKIGIICGSGLGSLA 146
            |..|.|...|.|...|...::||     :...| :||::.:.::|     ||:.||||||||:||
pombe     2 TATSFLHQAKQQPHHTEPYIKAL-----EAREY-IIEQVPEELSK-----PKVAIICGSGLGTLA 55

  Fly   147 DMIQDPKIFE--YEKIPNFPVSTVEGHAGRLVVGTL--EGATVMAMQGRFHFYEGYPLAKCSMPV 207
            ..:..| ::|  ||.||:|.||.|.|||.:|....|  :....|.:.||:|.|||||:...:.||
pombe    56 SGLSAP-VYEVPYEDIPHFHVSHVPGHASKLYFAFLGEKRVPTMILAGRYHSYEGYPIEATTFPV 119

  Fly   208 RVMKLCGVEYLFATNAAGGINPRFAVGDIMLMHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNS 272
            |:||:.|||.:..||||||:|..|.|||:|::.||:|..|.||.:||:|||...||.|||.|.::
pombe   120 RLMKVMGVEVMVVTNAAGGLNQGFKVGDLMILKDHINFPGLAGMNPLRGPNAHEFGVRFPPLSDA 184

  Fly   273 YNKDLINKAIEIAKAMGIESNIHVGVYSCLGGPNYETIAELKALRMMGVDAVGMSTVHEVITARH 337
            |:.:|.....:.|||..:...||.|.|:.:.||.:||.||.:.|.:||.|.||||||.||:.|||
pombe   185 YDLELRKLVYDAAKAHKVSRTIHEGCYAFVSGPCFETRAESRMLALMGADCVGMSTVPEVVVARH 249

  Fly   338 CDMKVFAFSLITNKCATEYSDKKDD------------EANHDEVMAV 372
            |.::|.|.||:||....|.|....|            .|||.||:.|
pombe   250 CGIRVLAISLVTNNVVVEESPSAKDLVEVDSNVMSKGAANHLEVLEV 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16758	NP_001261330.1	PRK08202	113..391	CDD:236183	123/276 (45%)
CG16758	NP_001261330.1	XapA	116..391	CDD:223084	122/273 (45%)
SPAC1805.16c	NP_593927.1	XapA	22..315	CDD:223084	125/287 (44%)
SPAC1805.16c	NP_593927.1	PNPH-PUNA-XAPA	42..313	CDD:130758	118/256 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	218	1.000	Domainoid score	I565
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H227
Inparanoid	1	1.050	223	1.000	Inparanoid score	I894
OMA	1	1.010	-	-		QHG58962
OrthoFinder	1	1.000	-	-		FOG0001804
OrthoInspector	1	1.000	-	-		otm47017
orthoMCL	1	0.900	-	-		OOG6_101826
Panther	1	1.100	-	-	LDO	PTHR11904
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2236
SonicParanoid	1	1.000	-	-		X1164
TreeFam	1	0.960	-	-
	14	13.860