DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16758 and Pnp

DIOPT Version :9

Sequence 1:	NP_001261330.1	Gene:	CG16758 / 38315	FlyBaseID:	FBgn0035348	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_038660.1	Gene:	Pnp / 18950	MGIID:	97365	Length:	289	Species:	Mus musculus

Alignment Length:	285	Identity:	147/285 - (51%)
Similarity:	194/285 - (68%)	Gaps:	2/285 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 EDTYPYEVIEEIADFITKGSGMRPKIGIICGSGLGSLADMIQDPKIFEYEKIPNFPVSTVEGHAG 173
            |:.:.||..|..|.::.:.:..||::.:|||||||.|...:::.:||:|.:|||||.|||:||||
Mouse     2 ENEFTYEDYETTAKWLLQHTEYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGHAG 66

  Fly   174 RLVVGTLEGATVMAMQGRFHFYEGYPLAKCSMPVRVMKLCGVEYLFATNAAGGINPRFAVGDIML 238
            |||.|.|.|...:.||||||.||||.|:|.:.||||..|.|||.|..||||||:||.|.||||||
Mouse    67 RLVFGLLNGRCCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDIML 131

  Fly   239 MHDHVNMLGFAGNSPLQGPNDPRFGPRFPALVNSYNKDLINKAIEIAKAMGIESNIHVGVYSCLG 303
            :.||:|:.||.|.:||:||||.|||.||||:.::|::|:..||....|.||.:..:..|.|..|.
Mouse   132 IRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFSAWKQMGEQRKLQEGTYVMLA 196

  Fly   304 GPNYETIAELKALRMMGVDAVGMSTVHEVITARHCDMKVFAFSLITNKCATEYSDKKDDEANHDE 368
            |||:||:||.:.|:|:|.||||||||.|||.||||.::||.|||||||...:|.:.  ::|||.|
Mouse   197 GPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYENL--EKANHME 259

  Fly   369 VMAVAKNRQKACCELVSRLIREIHL 393
            |:...|...:.....||.|:..|.|
Mouse   260 VLDAGKAAAQTLERFVSILMESIPL 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16758	NP_001261330.1	PRK08202	113..391	CDD:236183	144/277 (52%)
CG16758	NP_001261330.1	XapA	116..391	CDD:223084	142/274 (52%)
Pnp	NP_038660.1	XapA	11..283	CDD:223084	142/273 (52%)
		PNPH	26..280	CDD:273764	138/255 (54%)
		Phosphate binding. /evidence=ECO:0000250\|UniProtKB:P55859	84..86		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837086
Domainoid	1	1.000	282	1.000	Domainoid score	I1646
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H227
Inparanoid	1	1.050	298	1.000	Inparanoid score	I2697
Isobase	1	0.950	-	0	Normalized mean entropy	S669
OMA	1	1.010	-	-		QHG58962
OrthoDB	1	1.010	-	-		D1078969at2759
OrthoFinder	1	1.000	-	-		FOG0001804
OrthoInspector	1	1.000	-	-		otm43350
orthoMCL	1	0.900	-	-		OOG6_101826
Panther	1	1.100	-	-	O	PTHR11904
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2236
SonicParanoid	1	1.000	-	-		X1164
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750