DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	140/551 - (25%)
Similarity:	243/551 - (44%)	Gaps:	97/551 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WLTLITGALILLLTWD----FGRKRQRVLAF-EKSAIPGP----ISIPILGCGLQALHLGA---- 53
            ::.:|...|||.:.:|    :....:|:..| |:..|.||    ::..|:.......|..:
plant     9 YVLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCS 73

  Fly    54 ---ENI--------IGWVGEKFDKYGKTFRFW-------ILGESLIYTKDLQYFETILSSTTLLE 100
               .||        :.|    ..:|||.|..|       .|.|:.:..:.|.....:...:.|.:
plant    74 SIHHNIVPRLLPHYVSW----SKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGKSWLQQ 134

  Fly   101 KGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGK 165
            :|     .:.|:..|||::.|..||.:|.:...||....|:.|.:.|...:.:|.:.|||....:
plant   135 QG-----TKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEVGEE 194

  Fly   166 TAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRF--SR----RYN 224
              |::.:.:.....|:|:....|...:...:. |..:..|:.:. .|..|...|  ||    :||
plant   195 --VEIGEEMRRLTADIISRTEFGSSCDKGKEL-FSLLTVLQRLC-AQATRHLCFPGSRFLPSKYN 255

  Fly   225 WLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMA--L 287
                       |::.|....:.....::|..|:::|                 |||..|...  |
plant   256 -----------REIKSLKTEVERLLMEIIDSRKDSV-----------------EIGRSSSYGDDL 292

  Fly   288 LDILL-QSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLG 351
            |.:|| |...|...|:...|.:|..||.|.|.:|||..::..|..:|.:|..|..:.:|:::|.|
plant   293 LGLLLNQMDSNKNNLNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQVCG 357

  Fly   352 PDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYL-VLYYAH 415
            .|....|  .||..|..|:.||.|::|||||...:.|.|.:::::||..||...||:: ||...|
plant   358 QDGVPSV--EQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVLAIHH 420

  Fly   416 RDANYFPDPLSFRPERFLEDQEQGHNTFA----YVPFSAGPKNCIGQKFAVLEMKVLISKVLRFY 476
            .:..:..|...|.||||..      .:||    ::||:|||:|||||.||::|.|::::.::..:
plant   421 SNELWGEDANEFNPERFTT------RSFASSRHFMPFAAGPRNCIGQTFAMMEAKIILAMLVSKF 479

  Fly   477 ELLPLGEELK--PMLNFILRSASGINVGLRP 505
            . ..:.|..:  |::...::...|:.:.|:|
plant   480 S-FAISENYRHAPIVVLTIKPKYGVQLVLKP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	128/500 (26%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	140/551 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960