DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d20 and CYP86A4

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_171666.1	Gene:	CYP86A4 / 839347	AraportID:	AT1G01600	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	133/562 - (23%)
Similarity:	226/562 - (40%)	Gaps:	112/562 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITGALILLLT----WDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDK 66
            |:.|::|:..    |.:.::..|.|       .||...|:|| .|..|....:.:..|:.|....
plant     3 ISNAMLLVAIVTGYWLWFKRISRWL-------KGPRVWPLLG-SLPGLIEQRDRMHEWITENLRA 59

  Fly    67 YGKTFRFWILGESLIYTKDLQYFETILSSTTLLE-----------KGQLYE-YLRPFLNDGLLVS 119
            .|.|::..|.....:..|  |...|:......||           ||..:: .....|..|:..|
plant    60 CGGTYQTCIFAVPFLAKK--QGLVTVTCDPKNLEHMLKTRFDNYPKGPTWQSVFHDLLGQGIFNS 122

  Fly   120 TGRKWHARRKIFTHAFHFKVLEHY--------------------------VEIMDRHSSVMVDNL 158
            .|..|..:||.....|..:.|...                          |::.|....:..||:
plant   123 DGDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILATAQDNAEPVDLQDLILRLTFDNI 187

  Fly   159 RKVADGK---TAVDMLKYVSLA-ALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRF 219
            ..:|.||   |....|.....| |.|..|||::      |.              :|.|..|::.
plant   188 CGLAFGKDTRTCAPGLPENGFASAFDRATEASL------QR--------------FIIPKFMWKL 232

  Fly   220 SRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQ 284
            .:   || .|...:...:.|.:|   .::...||:.|::.:...:..||::    ...::.|:..
plant   233 KK---WL-GLGLEVSLSRSLGEI---DEYLAAVINTRKQELMSQQESGTHQ----RHDDLLSRFM 286

  Fly   285 MALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRV 349
            |.          ..:..||..::.....|:..|.||:|..:|...:.|..||.|:.:|..|:..|
plant   287 MK----------KTESYSDTFLQHVALNFILAGRDTSSVALSWFFWLITMHPTVEDKIVREICSV 341

  Fly   350 L----GPDASAPVTQA-----QLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-IPAN 404
            |    |.|..|..|:.     ::..|.||...|.||:||||.||...:|.:.:..:.|.| :||.
plant   342 LIETRGTDDVASWTEEPLGFDEIDRLVYLKAAISETLRLYPSVPEDSKHVENDDVLPDGTFVPAG 406

  Fly   405 TSIYLVLYYAHR-DANYFPDPLSFRPERF---LEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEM 465
            :|:...:|.|.| .:.:..|.|.|.|||:   ::.:...|:.:.:|.|:|||:.|:|:..|.|:|
plant   407 SSVTYSIYAAGRMKSTWGEDCLEFNPERWISPIDGKFINHDQYRFVAFNAGPRICLGKDLAYLQM 471

  Fly   466 KVLISKVLRFYELLPL-GEELKPMLNFILRSASGINVGLRPR 506
            |.:.:.||..:.|..: |.:::..::..|...:|:.|.|..|
plant   472 KTIAAAVLLRHRLTVVPGHKVEQKMSLTLFMKNGLLVNLYKR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	122/515 (24%)
CYP86A4	NP_171666.1	PLN03195	5..513	CDD:215627	131/558 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920