DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP87A2

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001184974.1	Gene:	CYP87A2 / 837830	AraportID:	AT1G12740	Length:	478	Species:	Arabidopsis thaliana

Alignment Length:	556	Identity:	122/556 - (21%)
Similarity:	219/556 - (39%)	Gaps:	128/556 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWLTLITGALILL------LTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLG-AENIIG 58
            ||..||..:|:|:      .:|...:.|.::       .||.:..|:||..:|..... ..:|..
plant     1 MWALLIWVSLLLISITHWVYSWRNPKCRGKL-------PPGSMGFPLLGESIQFFKPNKTSDIPP 58

  Fly    59 WVGEKFD------KYGKTFRFWILGESLIYT--KDLQYFETILSSTTLLEKGQLYEYLRPFLNDG 115
            ::.|:..      :||..|:..::|..:|.:  .||.||       ...::|:.::...|   |.
plant    59 FIKERVKNDVDMCRYGPIFKTNLVGRPVIVSTDADLSYF-------VFNQEGRCFQSWYP---DT 113

  Fly   116 LLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALD 180
            .....|:|    .....|.|.:|.|::.|..:..|     |.|:|         ||..|.:.|
plant   114 FTHIFGKK----NVGSLHGFMYKYLKNMVLTLFGH-----DGLKK---------MLPQVEMTA-- 158

  Fly   181 VITEAAMGVQVNAQNDPDFPYIK----------ALKSVVYIQPDRMFRFSRRYNWL--------F 227
                   ..::...::.|...:|          ..|.::...||:... :.|.|::        |
plant   159 -------NKRLELWSNQDSVELKDATASMIFDLTAKKLISHDPDKSSE-NLRANFVAFIQGLISF 215

  Fly   228 PLAAP--LLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDI 290
            |...|  ..|:.|....:.| .....::.||||..|:..:|                    ..|.
plant   216 PFDIPGTAYHKCLQGRAKAM-KMLRNMLQERRENPRKNPSD--------------------FFDY 259

  Fly   291 LLQSSINNQPLSDADIREEVD-----TFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVL 350
            :::.......:    :.||:.     ..:|...:|||..::.|:..::..|||.:|:.||.:.:|
plant   260 VIEEIQKEGTI----LTEEIALDLMFVLLFASFETTSLALTLAIKFLSDDPEVLKRLTEEHETIL 320

  Fly   351 --GPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYY 413
              ..||.:.:|..:.:.:.|....|.||.||...||||.|.|.::::..|.||||..::.:....
plant   321 RNREDADSGLTWEEYKSMTYTFQFINETARLANIVPAIFRKALRDIKFKDYTIPAGWAVMVCPPA 385

  Fly   414 AHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL 478
            .|.:...:.|||.|.|.|: |..:..:.:..::.|..|.:.|:|..|..|:|...:..::..|.
plant   386 VHLNPEMYKDPLVFNPSRW-EGSKVTNASKHFMAFGGGMRFCVGTDFTKLQMAAFLHSLVTKYR- 448

  Fly   479 LPLGEELK-------PMLNFILRSASGINVGLRPRK 507
               .||:|       |.|.|    .:|.:|.|..::
plant   449 ---WEEIKGGNITRTPGLQF----PNGYHVKLHKKR 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	111/501 (22%)
CYP87A2	NP_001184974.1	p450	4..475	CDD:299894	120/549 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920