DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d20 and CYP86A1

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_200694.1	Gene:	CYP86A1 / 836003	AraportID:	AT5G58860	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	123/565 - (21%)
Similarity:	207/565 - (36%)	Gaps:	124/565 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TLITG----ALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKF 64
            :::||    ||.:...|.:         |....:.||..:|.:| .|..|......|..|:.:..
plant     6 SILTGYAVAALSVYALWFY---------FLSRRLTGPKVLPFVG-SLPYLIANRSRIHDWIADNL 60

  Fly    65 DKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLE-----------KGQLYE-YLRPFLNDGLL 117
            ...|.|::...:  .:.:....|.|.|:......:|           ||.::. .....|..|:.
plant    61 RATGGTYQTCTM--VIPFVAKAQGFYTVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIF 123

  Fly   118 VSTGRKWHARRKIFTHAFHFKVLEHY--------------------------VEIMDRHSSVMVD 156
            .|.|..|..:||.....|..:.|...                          |::.|....:..|
plant   124 NSDGDTWLMQRKTAALEFTTRTLRQAMARWVNGTIKNRLWLILDRAVQNNKPVDLQDLFLRLTFD 188

  Fly   157 NLRKVADGK----TAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMF 217
            |:..:..||    .::|:.......|.|..|||                  .||.::|
plant   189 NICGLTFGKDPETLSLDLPDNPFSVAFDTATEA------------------TLKRLLY------- 228

  Fly   218 RFSRRYNWLFPLAAPL-LHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGS 281
               ..:.|....|..: ...:|...:.|:..:.:..|                      ||...|
plant   229 ---TGFLWRIQKAMGIGSEDKLKKSLEVVETYMNDAI----------------------DARKNS 268

  Fly   282 KSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEEL 346
            .|...|...|.:..:|...|....::.....|:..|.||:|..:|...:.:..:.||:.:|..||
plant   269 PSDDLLSRFLKKRDVNGNVLPTDVLQRIALNFVLAGRDTSSVALSWFFWLVMNNREVETKIVNEL 333

  Fly   347 QRVL----GPD----ASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-IP 402
            ..||    |.|    ...|:...:...|.||...:.||:||||.||...::...:..:.|.| :|
plant   334 SMVLKETRGNDQEKWTEEPLEFDEADRLVYLKAALAETLRLYPSVPQDFKYVVDDDVLPDGTFVP 398

  Fly   403 ANTSIYLVLYYAHRDANYF-PDPLSFRPERFL----EDQEQGHNTFAYVPFSAGPKNCIGQKFAV 462
            ..:::...:|...|....: .|.|.|||||:|    |..|...:.:.:|.|:|||:.|:|:..|.
plant   399 RGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAY 463

  Fly   463 LEMKVLISKVLRFYELLPL-GEELKPMLNFILRSASGINVGLRPR 506
            .:||.:.|.||..|.:.|: |..::..::..|...:|:.|.|:||
plant   464 NQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLRVYLQPR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	111/516 (22%)
CYP86A1	NP_200694.1	CYP86A	70..501	CDD:410687	102/482 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920