DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d20 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	119/474 - (25%)
Similarity:	206/474 - (43%)	Gaps:	95/474 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 QALHLGAENIIGW-----VGEKFDKYGKTFRFWILGESLIYTKDLQYFETI--------LSSTTL 98
            :|.|...:|||..     :...||.:.|.:     |....|:..|:....|        ||.|..
plant    68 EAKHCSGDNIISHDYSSSLFPHFDHWRKQY-----GRIYTYSTGLKQHLYINHPEMVKELSQTNT 127

  Fly    99 LEKGQ---LYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRK 160
            |..|:   :.:.|.|.|.:|::.|.|..|..:|:|..:.|....::..|.:|...:..|::...:
plant   128 LNLGRITHITKRLNPILGNGIITSNGPHWAHQRRIIAYEFTHDKIKGMVGLMVESAMPMLNKWEE 192

  Fly   161 VA--DGKTAVDM-----LKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFR 218
            :.  .|:...|:     ||.||   .|||.:|..|... ::....|..|:.|.:.: .:...:||
plant   193 MVKRGGEMGCDIRVDEDLKDVS---ADVIAKACFGSSF-SKGKAIFSMIRDLLTAI-TKRSVLFR 252

  Fly   219 FSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERR------ETVRRAKADGTYRPLSLGDA 277
            |                          :.|||.|...::      :.:........:..:...:.
plant   253 F--------------------------NGFTDMVFGSKKHGDVDIDALEMELESSIWETVKEREI 291

  Fly   278 EIGSKSQMALLDILLQSSINNQPLSDADI-------REEVD---TFMFEGDDTTSSGVSHALYAI 332
            |.....:..|:.::|:.::.:   .|.::       |..||   :..|.|.|:|:..||..|..:
plant   292 ECKDTHKKDLMQLILEGAMRS---CDGNLWDKSAYRRFVVDNCKSIYFAGHDSTAVSVSWCLMLL 353

  Fly   333 ARHPEVQQRIFEELQRVLG------PDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQ 391
            |.:|..|.:|.:|   :|.      |||.:      :.:||.:..||:||||||||.|.:||.|.
plant   354 ALNPSWQVKIRDE---ILSSCKNGIPDAES------IPNLKTVTMVIQETMRLYPPAPIVGREAS 409

  Fly   392 KELEIGDKTIPANTSIYLVLYYAHRDANYF-PDPLSFRPERFLEDQEQG-HNTFAYVPFSAGPKN 454
            |::.:||..:|....|:.::...|||...: ||...|:||||.|...:. ....:|:||..||:.
plant   410 KDIRLGDLVVPKGVCIWTLIPALHRDPEIWGPDANDFKPERFSEGISKACKYPQSYIPFGLGPRT 474

  Fly   455 CIGQKFAVLEMKVLISKVL 473
            |:|:.|.::|:|||:|.::
plant   475 CVGKNFGMMEVKVLVSLIV 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	119/474 (25%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	119/474 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960