DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP96A12

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_195661.1	Gene:	CYP96A12 / 830105	AraportID:	AT4G39510	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	122/505 - (24%)
Similarity:	224/505 - (44%)	Gaps:	73/505 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PILGC---GLQALHLGAENIIGWVGEKFDKYGKTFRF---WILGESLIYTKDLQYFETILSST-T 97
            |::|.   .|..||    .|..:..|..:....||.|   |.....:::|.|......||||. :
plant    36 PVIGMLPGFLMVLH----RIYNFGVEALEMSHLTFLFKGPWFAEMDMLFTVDPANIHYILSSNFS 96

  Fly    98 LLEKGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEH--YVEI-MDRHSSVMVDNL- 158
            ...||..::.:.....:.:..|....|..:||    |..| :|.|  :.:: :....|.:.|.|
plant    97 NYTKGADFKEVFDVFGEMIFSSDSELWKNQRK----AAQF-MLNHQGFQKLSLSATRSKLYDGLV 156

  Fly   159 ---RKVADGKTAVDMLKYVSLAALD----VIT---EAAMGVQVNAQNDPDFPYIKAL----KSVV 209
               .:..:.:..||:.:.......|    ::|   ..::.:::     |:..|.|||    :.:.
plant   157 PLFNQCCEEEKVVDLQQVFQRFTFDTTFFIVTGFDPKSLSIEM-----PEVEYAKALDDLGEGIF 216

  Fly   210 Y--IQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHD-FTDKVISERRETVRRAKADGTYRP 271
            |  |:|...::...|:.        |...:.:::.....| .:.|.|..:||.:|....|..
plant   217 YRHIKPKFFWKLQNRFG--------LGQEKRMTEADATFDRVSAKYILAKREEIRSQGIDHH--- 270

  Fly   272 LSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHP 336
             :.|::|....|.:. ||......:|  |..|..:|:.:..|...|.|||||.:|...:.::.:|
plant   271 -ANGESEDLLTSHIK-LDTTKYELLN--PSDDKFLRDTILAFNLAGRDTTSSALSWFFWLLSENP 331

  Fly   337 EVQQRIFEE-LQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEI---G 397
            :|..:|.:| :.:.:..|...  .|..|..|.||...:.|:||||||| |..|.:..:.::   |
plant   332 QVVTKIRKEIIDKNISKDGRN--GQENLDKLVYLHAALYESMRLYPPV-AFQRKSPIKPDVLPSG 393

  Fly   398 DKTIPANTSIYLVLYYAHR-DANYFPDPLSFRPERFLEDQEQG---H-NTFAYVPFSAGPKNCIG 457
            .| :.||:.|.:.|:...| .|.:..|...|:|||::  .|.|   | .:|.::.|:|||:.|.|
plant   394 HK-VEANSVIIIFLFALGRMRAVWGEDATEFKPERWV--SESGGLRHAPSFKFLSFNAGPRTCPG 455

  Fly   458 QKFAVLEMKVLISKVLRFYEL-LPLGEELKPMLNFILRSASGINVGLRPR 506
            ::.|:..||.::.::|:.|:: :..|::::|....:|....|:.|.:..|
plant   456 KQLAMTLMKTVVVEILQNYDIDVIKGQKIEPEPGLMLHMKHGLRVTITKR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	118/490 (24%)
CYP96A12	NP_195661.1	CYP86A	66..498	CDD:410687	111/462 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920