DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	139/549 - (25%)
Similarity:	228/549 - (41%)	Gaps:	104/549 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILG-----------CGLQALHLGAEN 55
            |:.|:...::        .||     |:|..|.||....:.|           ..|..|...:.:
plant    27 WILLLRPLML--------SKR-----FKKQGISGPKYKILYGNLSEIKKMKKEADLCVLDPNSND 78

  Fly    56 IIGWVGEKF----DKYGKTFRFWILGESLIYTKDLQYFETILSS----TTLLEKGQLYEYLRP-- 110
            |...|..::    .:||.||.||...:..||..:.:..:.:|||    |.:..|       ||
plant    79 IFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKFGFTIIPVK-------RPEV 136

  Fly   111 --FLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKV-ADGKT--AVDM 170
              ....||....|..|...|:|...||....|:...:.|...:..:.:..||. .:|:.  .:::
plant   137 FILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEWRKQRRNGEVLIKIEI 201

  Fly   171 LKYVSLAALDVITEAAMGVQ-------VNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFP 228
            .|.......|:|...|.|..       ..:|.:.:..||.:|.:|        |....:|   .|
plant   202 SKEFHKLTADIIATTAFGSSYAEGIELCRSQTELEKYYISSLTNV--------FIPGTQY---LP 255

  Fly   229 LAAPL----LHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLD 289
            ....|    ||:::.:.|:       ::|..|.::  :.|..|      .||         .||.
plant   256 TPTNLKLWELHKKVKNSIK-------RIIDSRLKS--KCKTYG------YGD---------DLLG 296

  Fly   290 ILLQSSINNQ---PLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLG 351
            ::|.::.:|:   .:...:|.||...|.:.|..|||..::.....::.|...|:::.||:....|
plant   297 VMLTAAKSNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEVFNECG 361

  Fly   352 PDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHR 416
            .| ..|.|.. ...||.::.|:.|::|||.||..|.|.|.:::::|...||..|||.:.|...||
plant   362 KD-KIPDTDT-FSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGHLEIPKGTSIIIPLLKMHR 424

  Fly   417 D-ANYFPDPLSFRPERFLEDQEQG--HNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL 478
            | |.:..|...|.|.||.....|.  |.. |.:|||.||:.||.:.||::|.|.:::.:|:.::
plant   425 DKAIWGEDAEQFNPLRFENGISQATIHPN-ALLPFSIGPRACIAKNFAMVEAKTVLTMILQQFQ- 487

  Fly   479 LPLGEELK--PMLNFILRSASGINVGLRP 505
            |.|..|.|  |:.:|.|....|:.|.|.|
plant   488 LSLSPEYKHTPVDHFDLFPQYGLPVMLHP 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	127/503 (25%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	139/549 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960