DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP86A2

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_191946.1	Gene:	CYP86A2 / 828019	AraportID:	AT4G00360	Length:	553	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	135/542 - (24%)
Similarity:	224/542 - (41%)	Gaps:	109/542 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRFWILGESLIYTKDLQ 87
            ||:..:.|    ||...|:|| .|..|....:.:..|:.|.....|.|::..|.....:..|  |
plant    21 QRISRWLK----GPRVWPVLG-SLPGLIEQRDRMHDWITENLRACGGTYQTCICAVPFLAKK--Q 78

  Fly    88 YFETILSSTTLLE-----------KGQLYE-YLRPFLNDGLLVSTGRKWHARRKIFTHAFHF--- 137
            ...|:......:|           ||..:: ....||..|:..|.|..|..:||  |.|..|
plant    79 GLVTVTCDPKNIEHMLKTRFDNYPKGPTWQAVFHDFLGQGIFNSDGDTWLFQRK--TAALEFTTR 141

  Fly   138 -------------------KVLE----HY--VEIMDRHSSVMVDNLRKVADGK---TAVDMLKYV 174
                               .:||    :|  |::.|....:..||:..:|.||   |....|...
plant   142 TLRQAMGRWVNRGIKLRFCPILETAQNNYEPVDLQDLILRLTFDNICGLAFGKDTRTCAPGLPEN 206

  Fly   175 SLA-ALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQL 238
            ..| |.|..|||::      |.              :|.|:.::|..:   || .|...:...:.
plant   207 GFASAFDRATEASL------QR--------------FILPEFLWRLKK---WL-GLGLEVSLSRS 247

  Fly   239 LSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSD 303
            |.:|   ..:.|.||:.|::.:             |...|.|.:....||...::.  .:|..|:
plant   248 LGEI---DGYLDAVINTRKQEL-------------LSQRESGVQRHDDLLSRFMKK--KDQSYSE 294

  Fly   304 ADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVL----GPDASA----PVTQ 360
            ..:|.....|:..|.||:|..:|...:.|..||.|:.:|..|:..||    |.|.|:    |:..
plant   295 TFLRHVALNFILAGRDTSSVALSWFFWLITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEF 359

  Fly   361 AQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-IPANTSIYLVLYYAHR-DANYFPD 423
            .::..|.||...:.||:||||.||...:|...:..:.|.| :||.:|:...:|.|.| .:.:..|
plant   360 DEVDRLVYLKAALSETLRLYPSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGED 424

  Fly   424 PLSFRPERFLEDQE---QGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL-LPLGEE 484
            .|.|:|||::...:   ..|:.:.:|.|:|||:.|:|:..|.|:||.:.:.||..:.| :..|.:
plant   425 CLEFKPERWISPDDGKFVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHK 489

  Fly   485 LKPMLNFILRSASGINVGLRPR 506
            ::..::..|...:|:.|.:..|
plant   490 VEQKMSLTLFMKNGLLVNVHKR 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	128/516 (25%)
CYP86A2	NP_191946.1	CYP86A	67..504	CDD:410687	118/482 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920