DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP94B3

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_190421.1	Gene:	CYP94B3 / 824011	AraportID:	AT3G48520	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	542	Identity:	128/542 - (23%)
Similarity:	233/542 - (42%)	Gaps:	97/542 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFD-KYGKTFRF 73
            |..|:|..|..........:::...||.|.|::| .:.:.:.....::.|..|... ...:|...
plant    10 LAFLITIIFFLSSSSTKKVQENTTYGPPSYPLIG-SILSFNKNRHRLLQWYTELLRLSPSQTILV 73

  Fly    74 WILG--ESLIYTKDLQYFETILSSTTL-LEKGQLY-EYLRPFLNDGLLVSTGRKWHARRKIFTHA 134
            .:||  .::|.|..|. .|.||.:... ..||:.: :.|...|..|:....|..|.::||:.:|.
plant    74 PLLGNRRTIITTNPLN-VEYILKTNFFNFPKGKPFTDLLGDLLGGGIFNVDGHSWSSQRKLASHE 137

  Fly   135 FHFKVLEHYV-EIM-DRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDP 197
            |..:.|..:. |:: |...:.:|..|...||..|.||:...:...|.||:.:.::|.      ||
plant   138 FSTRSLRSFAFEVLKDEVENRLVPVLSTAADVGTTVDLQDVLKRFAFDVVCKVSLGW------DP 196

  Fly   198 DF--------PYIKALKSVVYIQPDR-------MFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHD 247
            |.        |.::|..:...|...|       :::..|..|    :.:   .|:|...||.:|.
plant   197 DCLDLTRPVNPLVEAFDTAAEISARRATEPIYAVWKTKRVLN----VGS---ERKLREAIRTVHV 254

  Fly   248 FTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDT 312
            ...:::        |||.    :.|.:|   .|::::..||...|.:..|.:.     :|:.|.:
plant   255 LVSEIV--------RAKK----KSLEIG---TGAEAKQDLLSRFLAAGHNGEA-----VRDMVIS 299

  Fly   313 FMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETM 377
            |:..|.||||:.::...:.:..:.:|:::|.||:.    |..|..:....|:::.|....:.|.|
plant   300 FIMAGRDTTSAAMTWLFWLLTENDDVERKILEEVD----PLVSLGLGFEDLKEMAYTKACLCEAM 360

  Fly   378 RLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRD-ANYFP------------DPLSFRP 429
            ||||||....:||     ..|..:|..|.:      ...| ..|||            |...|.|
plant   361 RLYPPVSWDSKHA-----ANDDVLPDGTRV------KRGDKVTYFPYGMGRMETLWGTDSEEFNP 414

  Fly   430 ERFLEDQEQGH--------NTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELK 486
            .|:. |.|.|.        :.:.:..|.|||:.|:|::.|.::||.::..||..:|::|:.:: :
plant   415 NRWF-DSEPGSTRPVLKPISPYKFPVFQAGPRVCVGKEMAFMQMKYVVGSVLSRFEIVPVNKD-R 477

  Fly   487 PMLNFILRS--ASGINVGLRPR 506
            |:...:|.:  |.|:.|.::.|
plant   478 PVFVPLLTAHMAGGLKVKIKRR 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	119/501 (24%)
CYP94B3	NP_190421.1	p450	46..501	CDD:386267	119/505 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920