DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP86C2

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_189243.1	Gene:	CYP86C2 / 822212	AraportID:	AT3G26125	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	123/523 - (23%)
Similarity:	220/523 - (42%)	Gaps:	88/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRF---WILGESLIYTK---DLQYFETILS 94
            |:..|:.|. .....|...::.|||.....|...||.:   |..|.....|.   :::|.  :.:
plant    46 PVQWPVFGI-TPEFFLHVHDMFGWVTRCLTKSRGTFPYQGIWFSGSYGAMTSVPANIEYM--LKT 107

  Fly    95 STTLLEKGQLY-EYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDN- 157
            :.....||:.| |..|..|.||:..:....|..:|:|.              |.:.||:..||:
plant   108 NFKNFPKGEFYKERFRDLLEDGIFNADDESWKEQRRII--------------ITEMHSTRFVDHS 158

  Fly   158 -----------LRKVAD----GKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKS 207
                       |.||.:    .:.|.|:.:.:.....|.|..|.:|......:| |.|::...|:
plant   159 FQTTRDLIERKLLKVMESFSKSQEAFDLQEILLRLTFDNICIAGLGDDPGTLDD-DLPHVPFAKA 222

  Fly   208 VVYIQPDRMFRFS-RRYNW----LFPLAAPLLHRQLLSDIRVMHDFTDKVISER------RETVR 261
            ........:|||. ..:.|    .|.:.   ..:.|...:..:|:|.||::.||      :.|:.
plant   223 FEEATESTLFRFMIPPFVWKPMKFFDIG---YEKGLREAVETVHNFIDKMVVERIAMLKDQGTLA 284

  Fly   262 RAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVS 326
            .:|:|...|.:.:...:.|.:               |...:....|:...:|:..|.||:|..::
plant   285 NSKSDVLSRLIQIESHKRGDE---------------NDRFTAKFFRQFCTSFILAGRDTSSVALT 334

  Fly   327 HALYAIARHPEVQQRIFEELQRVLG--------------PDASAPVTQAQLQDLKYLDCVIKETM 377
            ...:.|.:||||:.:|..|::.:|.              .::|...|..:|.|:.||...:.|::
plant   335 WFFWLITKHPEVETKILHEIREILNQREKNKYKLDETGEKESSRHFTVKELNDMVYLQAALSESL 399

  Fly   378 RLYPPVPAIGRHAQKELEIGDKT-IPANTSIYLVLYYAHR-DANYFPDPLSFRPERFLE-DQEQG 439
            |||||:|...:.|.:|....|.| :...:.:|..:|...| ::.:..|...|:|||::: .|...
plant   400 RLYPPIPMEMKQATEEDVFPDGTFLRKGSRVYFSVYAMGRMESIWGKDCEMFKPERWIQGGQYVS 464

  Fly   440 HNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL-LPLGEELKPMLNFILRSASGINVGL 503
            .:.|.||.|:|||:.|:|:.||.|:||::.:.:|..|.: :.....:.|.:...|....|:.|.:
plant   465 DDQFKYVVFNAGPRLCLGKTFAYLQMKMVAASILLNYSIKVDQDHVVVPRVTTTLYMKHGLKVRI 529

  Fly   504 RPR 506
            .||
plant   530 TPR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	118/508 (23%)
CYP86C2	NP_189243.1	PLN03195	42..533	CDD:215627	123/523 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_114749
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810