DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP86A8

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_182121.1	Gene:	CYP86A8 / 819205	AraportID:	AT2G45970	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	134/561 - (23%)
Similarity:	225/561 - (40%)	Gaps:	117/561 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGK 69
            :|..|:.....|         |.|....:.||...|||| .|..|....|.:..|:.:.......
plant     8 MILSAITAYFLW---------LTFISRCLKGPRVWPILG-SLPGLIENCERMHDWISDNLRACSG 62

  Fly    70 TFRFWILGESLIYTKDLQYFETILSSTTLLE-----------KGQLYE-YLRPFLNDGLLVSTGR 122
            |::..|.....:..|  |...|:......||           ||..:: .....|..|:..|.|.
plant    63 TYQTCICAIPFLAKK--QGLVTVTCDPRNLEHILKNRFDNYPKGPTWQAVFHDLLGQGIFNSDGD 125

  Fly   123 KWHARRKIFTHAFHF----------------------KVLEHY------VEIMDRHSSVMVDNLR 159
            .|..:||  |.|..|                      .:||:.      :::.|....:..||:.
plant   126 TWLFQRK--TAALEFTTRTLRQAMARWVNRAIKLRFLPILENARLGSEPIDLQDLLLRLTFDNIC 188

  Fly   160 KVADGK---TAVDMLKYVSLA-ALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFS 220
            .:..||   |....|...:.| |.|..|||::      |.              :|.|:.:::|.
plant   189 GLTFGKDPRTCAPGLPVNTFAVAFDRATEASL------QR--------------FILPEILWKFK 233

  Fly   221 RRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQM 285
            |   ||.......|.|.|:.    :.::..::|:.|:|.:.....:|.:..
plant   234 R---WLRLGLEVSLTRSLVQ----VDNYLSEIITTRKEEMMTQHNNGKHHD-------------- 277

  Fly   286 ALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVL 350
               |:|.:.....:..||..::.....|:..|.||:|..:|...:.|.:||.::.:|..|:..||
plant   278 ---DLLSRFIKKKESYSDETLQRVALNFILAGRDTSSVALSWFFWLITQHPAIEDKILREICTVL 339

  Fly   351 ----GPDAS----APVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKT-IPANTS 406
                |.|.:    .|::..:|..|.:|...:.||:||||.||...:.|.|:..:.|.| :||.:|
plant   340 VETRGDDVALWTDEPLSCEELDRLVFLKAALSETLRLYPSVPEDSKRAVKDDVLPDGTFVPAGSS 404

  Fly   407 IYLVLYYAHR-DANYFPDPLSFRPERFLEDQEQG----HNTFAYVPFSAGPKNCIGQKFAVLEMK 466
            |...:|.|.| .:.:..|.|.|:|||::...:.|    |:.|.:|.|:|||:.|:|:..|.|:||
plant   405 ITYSIYSAGRMKSTWGEDCLEFKPERWISQSDGGRFINHDPFKFVAFNAGPRICLGKDLAYLQMK 469

  Fly   467 VLISKVLRFYEL-LPLGEELKPMLNFILRSASGINVGLRPR 506
            .:.|.||..:.| :..|.:::..::..|....|:.|.:..|
plant   470 SIASAVLLRHRLTVVTGHKVEQKMSLTLFMKYGLLVNVHER 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	125/517 (24%)
CYP86A8	NP_182121.1	CYP86A	67..503	CDD:410687	115/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920