DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and CYP96A5

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_179782.1	Gene:	CYP96A5 / 816727	AraportID:	AT2G21910	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	117/535 - (21%)
Similarity:	236/535 - (44%)	Gaps:	77/535 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRF 73
            ||::...:.|       |..:||....|.:.|:||. |..:.:....|..:|.|..:....||.|
plant    12 ALLVFFFFHF-------LIHKKSHQITPRNWPVLGM-LPGVLVMLHRINDYVAEILEVSNLTFAF 68

  Fly    74 ---WILGESLIYTKDLQYFETILSST-TLLEKGQLYEYLRPFLNDGLLVSTGRKWHARRK----I 130
               |..|.:::.|.|....:.:.||. :..:||..::.:..||.:|:..:..:.|...||    :
plant    69 KGPWFSGMNMLITADPSNIQHVFSSNFSNYDKGPEFKEMFDFLGNGIFTADSKLWEDMRKSALVV 133

  Fly   131 FTH----AFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQV 191
            .:|    :|..:.:...::      :.:|..|...|:..|..|:.......|.||......|...
plant   134 LSHQGFQSFSLRTITCKIK------NGLVPVLDHFAEANTVFDLQDVFQRLAFDVTLTLVTGCDS 192

  Fly   192 NAQN--DPDFPYIKAL----KSVVY--IQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDF 248
            ::.:  .|...|.||:    :.|||  ::|..:::..   ||:     .|...:.:.:.....|.
plant   193 SSLSIEMPKNEYAKAMDDAEEVVVYRHVKPVVLWKLQ---NWI-----GLGEEKKMKEANAAFDR 249

  Fly   249 T-DKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMA-LLDILLQSSINN----QPLSDADIR 307
            : .|.||.:||.:....::            ||.::... ||.:.:...|:.    .|..|..::
plant   250 SCAKYISAKREEIISHHSN------------IGGEAHAEDLLSVYMNLDISKYELLNPNDDNFLK 302

  Fly   308 EEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCV 372
            :.:.:||..|.|..::.::...:.::::||...:|.:|:...| |.:...:...:|..:.||...
plant   303 DIIKSFMLAGRDAIATTLTWFFWLLSKNPEAVTKIRQEINTNL-PGSGMSLDADKLNKMVYLHGA 366

  Fly   373 IKETMRLYPPVPAIGRHAQKELEIGDKTIPA------NTSIYLVLYYAHRDANYF-PDPLSFRPE 430
            :.|::|||.|:|     .:::..|....:|:      |..|...:|...|..:.: .|...|:||
plant   367 LCESLRLYAPIP-----FERKTPIKQDVLPSGHMVDKNWKILFSVYALGRMRSVWGQDASEFKPE 426

  Fly   431 RFLEDQEQG--HN-TFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPL-GEELKPMLNF 491
            |::.::..|  |. :|.:..|::||:||:|:..:.|:||.:..:::|.|::..: |.:::|..:.
plant   427 RWISERNGGLKHEPSFKFFVFNSGPRNCLGKNLSFLQMKTVAVEIIRNYDIKVVEGHKIEPASSI 491

  Fly   492 ILRSASGINVGLRPR 506
            ||....|:.|.:..|
plant   492 ILHMKHGLKVTVSKR 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	106/495 (21%)
CYP96A5	NP_179782.1	p450	1..506	CDD:299894	116/533 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920