Protein Alignment Cyp4d20 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 126/538 - (23%)
• Similarity: 202/538 - (37%)
• Gaps: 126/538 - (23%)

  Fly     5 LITGALILL-------LTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWV-- 60
            |::.||:|.       |.|...|.:...|...|    |.:..|::|   :..|        |:
 Frog    19 LVSVALLLAVSQQLWQLRWAATRDKSCKLPIPK----GSMGFPLVG---ETFH--------WILQ 68

  Fly    61 GEKF-----DKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLN-DGLLVS 119
            |..|     :|||..|:..:||..||.....:....||.....|...:.....|..|. :.|..|
 Frog    69 GSDFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNSLANS 133

  Fly   120 TGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITE 184
            .|.....:||:|:..|..:.||.|   :.:...|:.|.||..:....:::
 Frog   134 IGDIHRHKRKVFSKIFSHEALESY---LPKIQLVIQDTLRVWSSNPESIN--------------- 180

  Fly   185 AAMGVQVNAQNDPDFPYIKALKSVVYIQPDRM-FRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDF 248
                                    ||.:..:: ||.:.|....|.|:    ..:|....:|...|
 Frog   181 ------------------------VYCEAQKLTFRMAIRVLLGFRLS----DEELSQLFQVFQQF 217

  Fly   249 TDKVIS--------------ERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQS----- 294
            .:.|.|              ..||.:.::........|.    ....|.....||||::|
 Frog   218 VENVFSLPVDVPFSGYRRGIRAREMLLKSLEKAIQEKLQ----NTQGKDYADALDILIESGKEHG 278

  Fly   295 -SINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQ--RVL--GPDA 354
             .:..|.|.|..:.     .:|....||:|..:..:..:.:||.|.:::.|||:  .:|  |...
 Frog   279 KELTMQELKDGTLE-----LIFAAYATTASASTSLIMQLLKHPSVLEKLREELRGNSILHNGCVC 338

  Fly   355 SAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDAN 419
            ...:....:..|.||||||||.:||:.||....|...:..|:....||...|:...:...|..|.
 Frog   339 EGALRVETISSLHYLDCVIKEILRLFSPVSGGYRTVLQTFELDGFQIPKGWSVLYSIRDTHDTAP 403

  Fly   420 YFPDPLSFRPERFLEDQ-EQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVL---ISKVLRFY---- 476
            .|.|...|.|:||.:|: |.....|.|:||..|.:||:|:..|.|.:|||   ::.:.||.
 Frog   404 VFKDVDVFDPDRFGQDRTEDKDGRFHYLPFGGGVRNCLGKHLAKLFLKVLAIELASMSRFELATR 468

  Fly   477 ---ELLPL-----GEELK 486
               :::|:     .:|||
 Frog   469 TFPKIMPVPVVHPADELK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	108/461 (23%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	115/493 (23%)