Protein Alignment Cyp4d20 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 565
• Identity: 177/565 - (31%)
• Similarity: 267/565 - (47%)
• Gaps: 120/565 - (21%)

  Fly     2 W-LTLITGALILL---LTWDFGRKRQRVLAFEKS----AIPGPISIP----ILGCGLQALHLG-- 52
            | |.|:.||..||   ||..:|       .||.|    ..|.|   |    |||      |||
Mouse    19 WLLLLLAGASCLLAYILTPIYG-------VFENSLRLRCFPQP---PKRNWILG------HLGLI 67

  Fly    53 ---AENIIGWVGEKFDKYGKTFR----FW-------------------ILGESLIYTKDLQYFET 91
               .|.::     ......:|||    :|                   :|..:|:..||..:
Mouse    68 QSSEEGLL-----YIQSLVRTFRDACCWWVGPLHPVIRIFHPAFIKPVVLAPALVAPKDTVF--- 124

  Fly    92 ILSSTTLLEKGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVD 156
                         |.:|:|:|.||||:|||.||...|::.|.||||.:|:.||::.:..:::|..
Mouse   125 -------------YRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHA 176

  Fly   157 NLRKVAD-GKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFS 220
            ..:::|. |...::|.:::||..||.:.:.......|.|..|. .||.|:..:..:       .:
Mouse   177 KWQRLASKGSAYLNMFEHISLMTLDSLQKCVFSFDSNCQEKPS-EYITAILELSTL-------VA 233

  Fly   221 RRYNWLFPLAAPLLHRQLL-----------SDIRVMHDFTDKVISERRETVRRAKADGTYRPLSL 274
            ||:..|      |||..|.           ...|::|||||.||.|||.|:           |..
Mouse   234 RRHQRL------LLHVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRRTL-----------LDQ 281

  Fly   275 GDAEI-GSKSQMALLD----ILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIAR 334
            |..:: .:|::...||    :||....:.:.|||.|||.|.|||||.|.|||:||:|..||.:||
Mouse   282 GGVDVLKAKAKAKTLDFIDVLLLSKDEHGKALSDEDIRAEADTFMFGGHDTTASGLSWILYNLAR 346

  Fly   335 HPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGD- 398
            |||.|:|..:|::.:|.......:....|..|.:|...|||::||:|||.||.|...:::.:.|
Mouse   347 HPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDG 411

  Fly   399 KTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVL 463
            :.||......:.::..|.:...:|||..:.|.||..|..:|.:..|::||||||:|||||.||:.
Mouse   412 RVIPKGVISRISIFGTHHNPAVWPDPEVYDPFRFDADNVKGRSPLAFIPFSAGPRNCIGQTFAMS 476

  Fly   464 EMKVLISKVLRFYELLPLGEELKPMLNFILRSASGINVGLRPRKA 508
            ||||.::..|..:.:||..:|.:.....|||:..|:.:.:.|..|
Mouse   477 EMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLKVEPLSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	152/473 (32%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	152/486 (31%)