Protein Alignment Cyp4d20 and Cyp4f14

DIOPT Version :9

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001191262.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 546
• Identity: 173/546 - (31%)
• Similarity: 267/546 - (48%)
• Gaps: 82/546 - (15%)

  Fly     2 WLTLITGALILLLTWDFGRKRQRVLAFEKS-----AIPGPISIP----ILGCGLQALHL------ 51
            |.||    |:|..:|...|...::.|..::     ..|.|   |    ::|      |:
Mouse    19 WKTL----LLLGASWILARILIQIYAAYRNYRHLHGFPQP---PKRNWLMG------HVGMVTPT 70

  Fly    52 --GAENIIGWVGEKFDKYGKTFRFWILGESLIYT---KDLQYFETIL--SSTTLLEKGQLYEYLR 109
              |.:.:...||    .|.:.|..||.....:.|   .|:  ..:||  |:...|:....|..|:
Mouse    71 EQGLKELTRLVG----TYPQGFLMWIGPMVPVITLCHSDI--VRSILNASAAVALKDVIFYSILK 129

  Fly   110 PFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVM-VDNLRKVADGKTAVDMLKY 173
            |:|.||||||.|.||...|::.|.||||.:|:.||:|.:..:::| ....|.::||...:||.::
Mouse   130 PWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISDGSARLDMFEH 194

  Fly   174 VSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQL 238
            |||..||.:.:.......|.| :....||.|:..:..:       .::|:.      .||:...|
Mouse   195 VSLMTLDSLQKCVFSFDSNCQ-EKSSEYIAAILELSAL-------VAKRHQ------QPLMFMDL 245

  Fly   239 LSDI-----------RVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLD--- 289
            |.::           .|:|:|||.||.||..|:          |....|..:.||::...||
Mouse   246 LYNLTPDGMRFRKACNVVHEFTDAVIRERHRTL----------PDQGLDDFLKSKAKSKTLDFID 300

  Fly   290 -ILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPD 353
             :||....:.:.|||.|||.|.|||||||.|||:||:|..||.:|||||.|:|..:|:|.:|...
Mouse   301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGR 365

  Fly   354 ASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRD 417
            ....:....|..|.:|...|||::||:|||..|.|...:::.:.| :|||......:.::..|.:
Mouse   366 EPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHN 430

  Fly   418 ANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLG 482
            .:.:|||..:.|.||..:..:..:..|::||||||:|||||.||:.||||.::..|..:.|||..
Mouse   431 PSVWPDPEVYDPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDD 495

  Fly   483 EELKPMLNFILRSASGINVGLRPRKA 508
            :|.:.....|||:..|:.:.:.|..|
Mouse   496 KEPRRQPELILRAEGGLWLRVEPLSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	159/492 (32%)
Cyp4f14	NP_001191262.1	p450	52..511	CDD:365848	162/497 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845233
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750