DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d20 and zgc:123299

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_021324190.1	Gene:	zgc:123299 / 641477	ZFINID:	ZDB-GENE-051120-33	Length:	501	Species:	Danio rerio

Alignment Length:	501	Identity:	138/501 - (27%)
Similarity:	225/501 - (44%)	Gaps:	79/501 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 IPGPISIP----ILGCG---LQALH----LGAENIIGWVGEKFDKYGKTFRFWILGESLIYTKDL 86
            ||||   |    :||..   .:||:    |..:..:.|.    :|||..:|.    .:|.|...:
Zfish    38 IPGP---PRDNFLLGHSPSLTKALYSDDSLIYDLFLQWA----EKYGPVYRI----NTLHYVTIV 91

  Fly    87 QY----FETILSSTTLLEKGQLYE-----YLRPFLNDGLLVSTGRK-WHARRKIFTHAFHFKVLE 141
            .|    .:||:.|....:...:|.     :.:.||..||:.:.... |:.:|:|...||....|.
Zfish    92 VYCPEATKTIMMSPKYTKDPFVYRRVFNLFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLR 156

  Fly   142 HYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKA-- 204
            ..:...|..|..::|.|.::|:.||...|...|:...||||.:.|.||.:|.....|.|:..|
Zfish   157 SLISTFDEMSERLMDKLEEIANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQNAVE 221

  Fly   205 --LKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIR----VMHDFTDKVISERRETVRRA 263
              ||.:.:...|.:||...: ||           :|:..:|    ::....:|.|..|:..|:.
Zfish   222 LCLKGMTFDVRDPLFRIIPK-NW-----------KLIQQVREATELLRKTGEKWIQNRKTAVKN- 273

  Fly   264 KADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVD---TFMFEGDDTTSSGV 325
                            |......:|..:|:|:......|..|..:.:|   ||...|.:||::.:
Zfish   274 ----------------GEDVPKDILTQILKSAEEQNVTSTEDFEQMLDNFVTFFMAGQETTANQL 322

  Fly   326 SHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHA 390
            |.|:..:.|:||:.:|...|:..|||  ....::...|..|.||..|:|||:||||..|...|..
Zfish   323 SFAIMELGRNPEIYKRAKAEVDEVLG--TKREISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWL 385

  Fly   391 QKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNC 455
            .:::.|....||...|:....:.:.|...:|.|||.|.|:||.|:..:.:  :.|.||:.||:.|
Zfish   386 HEDMIINGIKIPGGCSVMFNSFVSQRLEKFFKDPLKFDPKRFDENAPKPY--YTYYPFALGPRTC 448

  Fly   456 IGQKFAVLEMKVLISKVLRFYE--LLPLGEELKPMLNFILRSASGI 499
            |||.|:.:|.||:::|:|:.:|  |:| |:.........||..||:
Zfish   449 IGQVFSQMEAKVVLAKLLQRFEFSLVP-GQSFDIKDTGTLRPKSGV 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	133/492 (27%)
zgc:123299	XP_021324190.1	p450	39..495	CDD:306555	137/500 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920