Protein Alignment Cyp4d20 and Cyp4f1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 170/539 - (31%)
• Similarity: 272/539 - (50%)
• Gaps: 68/539 - (12%)

  Fly     2 WLTLIT-GA---LILLLTWDFG--RKRQRVLAF----EKSAIPGPISIPILGCGLQALHLGAENI 56
            |.||:. ||   |..:||..:.  |..:|:..|    :::.:.|.:.:      :.....|.:.:
  Rat    19 WQTLLLFGASWILAQILTQIYAAYRNFRRLRGFPQPPKRNWLMGHVGM------VTPTEQGLKEL 77

  Fly    57 IGWVGEKFDKYGKTFRFWILGESLIYT---KDLQYFETIL--SSTTLLEKGQLYEYLRPFLNDGL 116
            ...||    .|.:.|..||.....:.|   .|:  ..:||  |:...|:....|..|:|:|.|||
  Rat    78 TRLVG----TYPQGFLMWIGPMVPVITLCHSDI--VRSILNASAAVALKDVIFYTILKPWLGDGL 136

  Fly   117 LVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRK-VADGKTAVDMLKYVSLAALD 180
            |||.|.||...|::.|.||||.:|:.||:|.:..:::|....:: :::|.:.:||.::|||..||
  Rat   137 LVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVSLMTLD 201

  Fly   181 VITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDI--- 242
            .:.:.......|.| :....||.|:..:..:       .::|:.      .|||...||.::
  Rat   202 SLQKCVFSFDSNCQ-EKSSEYIAAILELSAL-------VAKRHQ------QPLLFMDLLYNLTPD 252

  Fly   243 --------RVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLD----ILLQSS 295
                    .::|:|||.||.|||.|:          |....|..:.||::...||    :||...
  Rat   253 GMRFHKACNLVHEFTDAVIRERRRTL----------PDQGLDEFLKSKAKSKTLDFIDVLLLTKD 307

  Fly   296 INNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQ 360
            .:.:.|||.|||.|.|||||||.|||:||:|..||.:|:|||.|:|..:|:|.:|.......:..
  Rat   308 EDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEW 372

  Fly   361 AQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDP 424
            ..|..|.:|...|||::||:|||..|.|...:::.:.| :|||......:.::..|.:.:.:|||
  Rat   373 DDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDP 437

  Fly   425 LSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPML 489
            ..:.|.||..:..:..:..|::||||||:|||||.||:.||||.::..|..:.|||..:|.:...
  Rat   438 EVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQP 502

  Fly   490 NFILRSASGINVGLRPRKA 508
            ..|||:..|:.:.:.|..|
  Rat   503 ELILRAEGGLWLRVEPLSA 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	152/454 (33%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	155/470 (33%)