Protein Alignment Cyp4d20 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 535
• Identity: 140/535 - (26%)
• Similarity: 254/535 - (47%)
• Gaps: 68/535 - (12%)

  Fly     2 W--LTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQ---ALHLGAENIIGWVG 61
            |  |..:...|::..:|..       ..|:|..||||.:||..|..|:   ..|:       :..
Zfish     8 WTLLAFLVALLVIYGSWPH-------RYFKKLGIPGPKTIPFFGTMLRYKDGFHV-------FDM 58

  Fly    62 EKFDKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPF-----LNDGLLVSTG 121
            :.|:|||:.:..:...:.::...|    :||:.:..:.|...|:...|.|     |.|.:.::..
Zfish    59 DCFEKYGRIWGIYDGRQPVLCIMD----QTIIKTVLIKECYSLFTNRRNFRLNGALYDAVSIAED 119

  Fly   122 RKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAA 186
            ..|...|.:.:.:|....|:....||.:||.::||::.|.|....:.|:.::....::||:|..|
Zfish   120 DDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTSTA 184

  Fly   187 MGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWL------FPLAAPLLHRQLLSDIRVM 245
            ..|.:::.|:|..|::..:|        :|.:|. ..|.|      ||..||:|.:.   |..:
Zfish   185 FSVDIDSLNNPKDPFVTNIK--------KMLKFD-LLNPLFLLIAFFPFMAPVLEKM---DFAL- 236

  Fly   246 HDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSI----------NNQP 300
              |...|.......:::.|:|...:.:    |:..:|.::..|.:::.|..          ..:.
Zfish   237 --FPTSVTDFFYAALQKIKSDRDTKTV----AKDNTKKRVDFLQLMVDSQTGVKHKSDGEHTEKG 295

  Fly   301 LSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQD 365
            |||.:|..:...|:|.|.:|:||.:|...|.:|.:||..:::.||:.... |: .|||....|..
Zfish   296 LSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF-PN-QAPVDYETLMS 358

  Fly   366 LKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPE 430
            :.|||..:.|::||||....:.|..:|.:||....||.:..:.:..|..|||.:|:.:|.||:||
Zfish   359 MDYLDAALSESLRLYPVAARLERVCKKTVEINGLLIPKDLVVMVPTYALHRDPDYWSEPESFKPE 423

  Fly   431 RFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPM---LNFI 492
            ||.:..::..:.:.|:||..||:||||.:||.:.||:.|.::|:.:::....|...|:   .|.:
Zfish   424 RFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNGL 488

  Fly   493 LRSASGINVGLRPRK 507
            |.....|.:.|:|||
Zfish   489 LSPKDPIKLKLQPRK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	118/456 (26%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	120/459 (26%)